195245-31-9

Upstream product

• 305834-23-5 3,4,5-tri-O-benzyl-1,2-dideoxy-L-lyxo-hex-1-enitol 
• 175844-96-9 2,3,4-Tri-O-benzyl-5,6-dideoxy-L-arabino-hex-5-enose 
• 4356-80-3 methyl 2,3,4-tri-O-benzyl-α-D-galactopyranoside 
• 176018-12-5 (2S,3R,4S,5R)-3,4,5-tris(benzyloxy)-2-(iodomethyl)-6-methoxytetrahydro-2H-pyran 
• 305834-18-8 (2S,3R,4S,5R)-3,4,5-tris(benzyloxy)-2-(iodomethyl)-6-methoxytetrahydro-2H-pyran 

Downstream Products

• 195245-37-5 (1S,2R,3S,4S)-1,2,3-tribenzyloxy-4-hydroxymethylcyclopentane 
• 144938-80-7 (1S,2R,3S,4S)-(-)-4-(Hydroxymethyl)cyclopentane-1,2,3-triol 

Relevant academic research and scientific papers

The cobalt-catalyzed oxygenative radical route from hexopyranosides to carbapentofuranoses

Cobalt-catalyzed radical cyclization/oxygenation of various 6-iodohex-1-enitols gave in one step the carbocyclic analogs of pentofuranoses. The reaction was run under very mild conditions and gave moderate to good yields of carbapentofuranoses within a few hours. All the possible 6-iodohex-1-enitol stereoisomers were prepared, and the influence of relative configurations and protecting groups was studied.

A new synthesis of carbapentofuranoses from carbohydrates

Carbafuranosides were synthesized in one step from various O-protected 1,2,6-trideoxy-6-iodo-hex-1-enitols by cobalt catalyzed 5-exo radical-cyclization under molecular oxygen. Yields were fair to good with interesting selectivities.