195325-66-7

Upstream product

• 3536-96-7 vinylmagnesium chloride 
• 1026493-36-6 {(S)-1-Formyl-2-[1-(2,4,6-trimethyl-benzenesulfonyl)-1H-indol-3-yl]-ethyl}-carbamic acid tert-butyl ester 
• 195325-55-4 {(S)-1-(Methoxy-methyl-carbamoyl)-2-[1-(2,4,6-trimethyl-benzenesulfonyl)-1H-indol-3-yl]-ethyl}-carbamic acid tert-butyl ester 
• 97530-05-7 (S)-tert-butyl (3-(1H-indol-3-yl)-1-(methoxy(methyl)amino)-1-oxopropan-2-yl)carbamate 
• 13139-14-5 Boc-Trp-OH 

Downstream Products

• 195325-67-8 (3R,4S)-4-tert-butyloxycarbonylamino-3-tetrahydropyranyloxy-5-3'-(N-mesitylene-2-sulfonyl)indolyl-1-pentene 
• 195325-69-0 (3S,4S)-4-tert-butyloxycarbonylamino-1,2-dihydroxy-3-tetrahydropyranyloxy-5-3'-(N-mesitylene-2-sulfonyl)indolylpentane 
• 195325-71-4 (E)-(4R,5S)-5-tert-Butoxycarbonylamino-4-hydroxy-6-[1-(2,4,6-trimethyl-benzenesulfonyl)-1H-indol-3-yl]-hex-2-enoic acid methyl ester 
• 195325-70-3 (E)-(4R,5S)-5-tert-Butoxycarbonylamino-4-(tetrahydro-pyran-2-yloxy)-6-[1-(2,4,6-trimethyl-benzenesulfonyl)-1H-indol-3-yl]-hex-2-enoic acid methyl ester 
• 195325-72-5 (E)-(4R,5S)-5-tert-Butoxycarbonylamino-4-methanesulfonyloxy-6-[1-(2,4,6-trimethyl-benzenesulfonyl)-1H-indol-3-yl]-hex-2-enoic acid methyl ester 

Relevant academic research and scientific papers

A highly stereoselective synthesis of the functionalized (E)-alkene dipeptide isostere of Trp-Val via organocyanocopper-Lewis acid mediated reaction

A stereocontrolled synthesis of the (e)-alkene dipeptide isostere of Trp-Val is described. The stereospecific α-alkylation of the δ-amino-γ- mesyloxy-α,β-unsaturated ester via the organocyanocopper-Lewis acid mediated reaction, based on 1,3-transfer of ch