195372-68-0Relevant academic research and scientific papers
An enantioselective route to trans-2,6-disubstituted piperidines
Chackalamannil, Samuel,Wang, Yuguang
, p. 11203 - 11210 (2007/10/03)
The synthesis of (S)-2-methyl tetrahydropyridine-N-oxide (4), a key intermediate for the enantioselective construction of trans-2,6-disubstituted piperidines via [3+2] nitrone cycloaddition reaction, is described. Nitrone 4 was elaborated to the fire ant venom alkaloid (+)-solenopsin-A (2) via intermediate 14.
