19556-54-8 Usage
Uses
Used in Antiviral Applications:
1-(5-chloro-5-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione is used as an antiviral agent for its ability to disrupt the synthesis of viral DNA and RNA, thereby inhibiting the replication and spread of viruses within host cells.
Used in Anticancer Applications:
In the field of oncology, 1-(5-chloro-5-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione is used as an anticancer agent, targeting the synthesis of cancerous cells' DNA and RNA. This action can lead to the suppression of tumor growth and the prevention of cancer progression.
Used in Pharmaceutical Synthesis:
1-(5-chloro-5-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione is used as a chemical building block in the synthesis of various pharmaceuticals, particularly those with antiviral and anticancer properties. Its unique structure and functional groups make it a versatile component in drug development.
Used in Drug Development Research:
1-(5-chloro-5-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione is also used in the research and development of new drugs and therapies, as its interaction with nucleic acids provides insights into potential treatments for a variety of diseases, including viral infections and cancer.
Used in the Chemical Industry:
1-(5-chloro-5-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione may be utilized in the chemical industry for the creation of novel compounds with specific applications, such as those with enhanced antiviral or anticancer properties, or for use in other therapeutic areas.
Check Digit Verification of cas no
The CAS Registry Mumber 19556-54-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,5,5 and 6 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 19556-54:
(7*1)+(6*9)+(5*5)+(4*5)+(3*6)+(2*5)+(1*4)=138
138 % 10 = 8
So 19556-54-8 is a valid CAS Registry Number.
19556-54-8Relevant academic research and scientific papers
Chlorination of nucleosides by N-chlorodiisopropylamine and triphenylphosphine
Zhou, Yi-Sui,Miao,Zhao, Yu-Fen
, p. 671 - 673 (2007/10/03)
The combination of N-chlorodiisopropylamine and triphenylphosphine (1) was exploited as a new method for chlorination of the hydroxyl group on the nucleosides. A possible mechanism involving an oxyphosphonium intermediate 2a and a phosphorane intermediate 2b was proposed based on the results from 31P NMR spectrum.
9-(4-METHOXYPHENYL)XANTHEN-9-THIOL: A USEFUL REAGENT FOR THE PREPARATION OF THIOLS
Marriott, Jonathan H.,Mottahedeh, Mina,Reese, Colin B.
, p. 7485 - 7488 (2007/10/02)
Treatment of 5'-chloro-5'-deoxynucleosides (5) with the conjugate base of 9-(4-methoxyphenyl)xanthen-9-thiol (3b), followed by acid-promoted removal of the 5'-S- group in the presence of pyrrole gives the corresponding 5'-deoxy-5'-mercaptonucleosides (7) in good yields.
