19559-59-2

Usage

Uses

Used in Cancer Treatment:
Potassium dichloroacetate is used as an anticancer agent for its potential to inhibit the proliferation of cancer cells and induce apoptosis. It may contribute to the regulation of glucose metabolism and mitochondrial function, which are essential for cancer cell survival and growth.
Used in Mitochondrial Function Regulation:
Potassium dichloroacetate is used to upregulate mitochondrial function, which can help in the prevention and treatment of cancer by enhancing the cell's ability to undergo apoptosis and reducing the energy supply for cancer cell growth.
Used in Glucose Metabolism Regulation:
Potassium dichloroacetate is used to promote the regulation of glucose metabolism, which may contribute to its anti-cancer effects by affecting the availability of glucose for cancer cells and altering the metabolic pathways involved in cancer progression.
Used in Pyruvate Dehydrogenase Complex Regulation:
Potassium dichloroacetate is used to regulate the activity of the pyruvate dehydrogenase complex, which is involved in the metabolism of glucose. Modulating its activity can potentially impact cancer cell metabolism and growth.
Note: While the provided materials highlight the potential of potassium dichloroacetate in cancer treatment and related areas, further research is needed to fully understand its mechanisms of action and potential clinical applications.

InChI:InChI=1/C2H2Cl2O2.K/c3-1(4)2(5)6;/h1H,(H,5,6);/q;+1/p-1

Upstream product

• 6134-66-3 ethyl 2,2-dichloroacetoacetate 
• 151-50-8 potassium cyanide 
• 535-15-9 ethyl 1,1-dichloroacetate 
• 18261-09-1 acetic acid-(1-ethoxy-2,2,2-trichloro-ethyl ester) 

Downstream Products

• 535-15-9 ethyl 1,1-dichloroacetate 
• 146509-64-0 bis-(4-amino-3,5-dimethyl-phenyl)-acetic acid 
• 40151-73-3 Dichloro-acetic acid [(3-chloro-phenyl)-isopropoxycarbonyl-amino]-methyl ester 
• 554-84-7 meta-nitrophenol 
• 79-43-6 dichloro-acetic acid 
• 15719-64-9 methylammonium carbonate 
• 67059-67-0 6-chloro-4-phenyl-[4H]-1,3-benzodioxin-2-carboxylic acid 
• 5616-65-9 1,3-dithiolane-2-carboxylic acid 
• 106-48-9 4-chloro-phenol 
• 108-43-0 3-monochlorophenol 

Relevant academic research and scientific papers

Iminophenylthiazolidines, process of preparation and method of use

A 2-iminophenyl thiazolidine having the formula STR1 wherein R is hydrogen or methyl; R1 is halo, nitro, cyano, C1 -C4 alkyl, C1 -C4 alkoxy, perhalomethyl, difluoromethyl, pentafluoroethyl, trifluoromethylthhio, difluoromethoxy, trifluoromethoxy, tetrafluoroethoxy, methylsulfonyl, C1 -C4 alkyloxyiminomethyl, benzyloxyiminomethyl, 1-(C1 -C4 alkyl)-oxyiminoethyl or 1-benzyloxyiminoethyl; R2 is hydrogen or halo; R3 and R4 are independently hydrogen, halo, nitro, cyano, C1 -C4 haloalkyl, C1 -C4 alkyl, C1 -C4 fluoroalkoxy, C1 -C4 alkoxy or C1 -C4 alkylthio; and X is hydrogen or halogen. Also disclosed is a process for making the compounds and a method of use which comprises applying the compound or composition to the locus where control is desired.