195720-15-1Relevant articles and documents
Antiviral substituted pyrimidinedione homocarbocyclic nucleoside derivatives and methods for the preparation thereof and compositions containing the same as active ingredients
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, (2008/06/13)
The present invention relates to novel compound of general formula (I) and pharmaceutically acceptable salts thereof, and process for the preparation of such derivatives and to pharmaceutical compositions containing the same as active ingredients. STR1 wherein R1, R2, and R3 represents independently hydrogen atom, halogen atom, C1 -C10 alkyl, C1 -C10 thioalkyl, C3 -C8 optionally substituted cyclicalkyl, unsaturated alkyl, substituted alkyl hydroxyl or aryl hydroxyl, C1 -C10 alkylamine, nitro, C1 -C4 lower ester, C1 -C4 lower alkoxy, C1 -C4 lower thioalkoxy; Z represents oxygen atom, sulfur atom, carbon atom and carbonyl group; X represents oxygen atom, sulfur atom; n represents an integer of 1-3; and (sub)cycloalk(en)yl represents STR2 in which R4 and R5 represents independently hydrogen atom, hydroxymethyl, protected hydroxymethyl, benzyl, substituted carbonyl, substituted alkylsulfonyl or arylsulfonyl, substituted silyl or the like.
