19577-80-1Relevant academic research and scientific papers
Identification of a new class of small molecule C5a receptor antagonists
Chen, Jack J.,Cole, Derek C.,Ciszewski, Greg,Crouse, Kimberly,Ellingboe, John W.,Nowak, Pawel,Tawa, Gregory J.,Berstein, Gabriel,Li, Wei
scheme or table, p. 662 - 664 (2010/06/21)
C5a is a terminal product of the complement cascade that activates and attracts inflammatory cells including granulocytes, mast cells and macrophages via a specific GPCR, the C5a receptor (C5aR). Inhibition of C5a/C5aR interaction has been shown to be eff
New gas-phase cascade reactions of stabilized phosphorus ylides leading to ring-fused indoles and to quinolines
Aitken, R. Alan,Murray, Lorna
supporting information; experimental part, p. 9781 - 9783 (2009/04/06)
(Chemical Equation Presented) Gas-phase cyclization processes of stabilized phosphorus ylides bearing a suitably substituted 2-aminophenyl group lead efficiently either to 3-substituted quinolines or benzo[c]-carbazole and heterocyclic-fused analogues depending on the substituents present.
