19578-69-9

Usage

Synonyms

Benzyl 2,4-dichlorophenyl ether

Structure

Benzyl ether derivative of 2,4-dichlorophenol

Synthesis

Reaction of benzyl chloride and 2,4-dichlorophenol

Applications

a. Pharmaceutical synthesis
b. Agrochemical synthesis
c. Dye synthesis
d. Insecticidal properties research

Color

White solid

Melting point

High

Solubility

Low in water

Suitability

Good for various chemical reactions and applications

Upstream product

• 3757-76-4 sodium 2,4-dichlorophenolate 
• 100-44-7 benzyl chloride 
• 120-83-2 2,4-dichlorophenol 
• 100-58-3 phenylmagnesium bromide 
• 1078-58-6 diphenylzinc 
• 94-75-7 2,4-Dichlorophenoxyacetic acid 

Downstream Products

• 190199-40-7 1-(2,4-dichlorophenyl)-1H-imidazole 

Relevant academic research and scientific papers

Redox-Active Esters in Fe-Catalyzed C-C Coupling

Cross-couplings of alkyl halides and organometallic species based on single electron transfer using Ni and Fe catalyst systems have been studied extensively, and separately, for decades. Here we demonstrate the first couplings of redox-active esters (both isolated and derived in situ from carboxylic acids) with organozinc and organomagnesium species using an Fe-based catalyst system originally developed for alkyl halides. This work is placed in context by showing a direct comparison with a Ni catalyst for >40 examples spanning a range of primary, secondary, and tertiary substrates. This new C-C coupling is scalable and sustainable, and it exhibits a number of clear advantages in several cases over its Ni-based counterpart.

Silica-Supported Oligomeric Benzyl Phosphate (Si-OBP) and Triazole Phosphate (Si-OTP) Alkylating Reagents

The syntheses of silica-supported oligomeric benzyl phosphates (Si-OBPn) and triazole phosphates (Si-OTPn) using ring-opening metathesis polymerization (ROMP) for use as efficient alkylating reagents is reported. Ease of synthesis and grafting onto the surface of norbornenyl-tagged (Nb-tagged) silica particles has been demonstrated for benzyl phosphate and triazole phosphate monomers. It is shown that these silica polymer hybrid reagents, Si-OBPn and Si-OTPn, can be used to carry out alkylation reactions with an array of different nucleophiles to afford the corresponding benzylated and (triazolyl)methylated products in good yield and high purity.

PESTICIDAL SUBSTITUTED PHENYLETHERS

The invention relates to the use of phenylether derivatives of formula (I), to compositions thereof for the control of pests, including arthropods and helminths.