195832-14-5

Upstream product

• 200644-47-9 (S)-3,4-Dihydro-1H-isoquinoline-2,3-dicarboxylic acid 2-benzyl ester 3-methyl ester 
• 501-53-1 benzyl chloroformate 
• 18881-17-9 (S)-3-hydroxymethyl-1,2,3,4-tetrahydroisoquinoline 
• 79815-19-3 methyl (3S)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate 
• 79261-58-8 (S)-3,4-dihydro-1H-isoquinoline-2,3-dicarboxylic acid 2-benzyl ester 
• 74163-81-8 L-Tic-OH 

Downstream Products

• 54329-61-2 3-aminomethyl-1,2,3,4-tetrahydroisoquinoline dihydrochloride 
• 885273-85-8 [(3S)-1,2,3,4-tetrahydroisoquinoline-3-yl-methyl]carbamic acid tert-butyl ester 
• 195832-15-6 S-3-formyl-3,4-dihydro-1H-isoquinoline-2-carboxylic acid benzyl ester 
• 762245-24-9 (2-amino-4-benzyloxy-5-methoxy-phenyl)-[3-(bis-ethylsulfanyl-methyl)-3,4-dihydro-1H-isoquinolin-2-yl]-methanone 
• 762245-23-8 (4-benzyloxy-5-methoxy-2-nitro-phenyl)-[3-(bis-ethylsulfanyl-methyl)-3,4-dihydro-1H-isoquinolin-2-yl]-methanone 
• 762245-25-0 2-benzyloxy-12-hydroxy-3-methoxy-11,11a,12,13-tetrahydro-6H-5a,13-diaza-benzo[4,5]cyclohepta[1,2-b]naphthalen-5-one 

Relevant academic research and scientific papers

Novel derivatives of indole and pyrrole, method for the production thereof and pharmaceutical compositions containing same

The invention relates to compounds of formula (I), wherein Ra, Rb, Rc, Rd, R3, R4, R5, A1, A2, T and W are as defined in the description. The invention also relates to drugs containing same.

INDOLE AND PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Compounds of formula (I): wherein Ra, Rb, Rc, Rd, R3, R4, R5, A1, A2, T and W are as defined in the description. Medicinal products containing the same whic

PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Compounds of formula (I): wherein A1, A2, Ra, Rb, Rc, Rd, R3, R4, R5 and T are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.

NEW ISOINDOLINE OR ISOQUINOLINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Compounds of formula (I): (I) wherein Het, R3, R4, R5, R7, R8, R9, T, p, p', q, and q' are as defined in the description are pro-apoptotic agents useful in the treatment of cancers and of a

Synthesis of (S)-3-aminoethyl-1,2,3,4-tetrahydroisoquinoline (TIQ-diamine) via the Mitsunobu protocol

The synthesis of (S)-3-Aminoethyl-1, 2, 3, 4-tetrahydroisoquinoline (TIQ-diamine) was successfully achieved via the Mitsunobu protocol. The method from earlier reports utilizing aminolysis of commercially available TIQ-amino methyl ester, and reduction of

TETRAHYDRO ISOQUINO LINEALKANOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

The present invention provides novel 1,2,3,4-tetrahydro isoquinoline carbamate and thiocarbamate derivatives represented by Formula (I), wherein: X1 and X2 are the same or different from each other and independently represent a member selected from the gr

Synthesis of a novel tetrahydroisoquinolino[2,1-c][1,4]benzodiazepine ring system with DNA recognition potential

The first stereospecific synthesis of a novel tetrahydroisoquinolino[2,1-c] [1,4]benzodiazepine ring system with DNA recognition potential starting from (S)-1,2,3,4-tetrahydroisoquinoline carboxylic acid has been reported. We report the first stereospecif

Isoquinolines useful as analgesics

PCT No. PCT/SE97/00315 Sec. 371 Date Oct. 6, 1997 Sec. 102(e) Date Oct. 6, 1997 PCT Filed Feb. 25, 1997 PCT Pub. No. WO97/31940 PCT Pub. Date Sep. 4, 1997The present invention is directed to compounds that act as analgesics and that have the structure of

Tetrahydroisoquinolinealkanol derivatives and pharmaceutical compositions containing same

The present invention provides novel 1,2,3,4-tetrahydroisoquinoline carbamate and thiocarbamate derivatives represented by Formula I STR1 wherein: X1 and X2 are the same or different from each other and independently represent a a me