19591-45-8

Basic information

• Product Name: 9,10-Dihydro-5,8-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid
• Synonyms: 9,10-Dihydro-5,8-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid;Quinizarin-6-carboxylic acid
• CAS NO: 19591-45-8
• Molecular Formula: C15H8O6
• Molecular Weight: 284.2204
• Mol File: 19591-45-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 607.2°Cat760mmHg
• Flash Point: 335°C
• Appearance: /
• Density: 1.687g/cm³
• Vapor Pressure: 1.35E-15mmHg at 25°C
• Refractive Index: 1.76
• CAS DataBase Reference: 9,10-Dihydro-5,8-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 9,10-Dihydro-5,8-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid(19591-45-8)
• EPA Substance Registry System: 9,10-Dihydro-5,8-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid(19591-45-8)

Safety Data

• Hazardous Substances Data: 19591-45-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H8O6/c16-9-3-4-10(17)12-11(9)13(18)7-2-1-6(15(20)21)5-8(7)14(12)19/h1-5,16-17H,(H,20,21)

Upstream product

• 7664-93-9 sulfuric acid 
• 117-78-2 anthraquinone-2-carboxylic acid 
• 13460-50-9 metaboric acid 
• 123-31-9 hydroquinone 
• 552-30-7 trimellitic Anhydride 

Relevant articles and documents

Anthraquinones related to rhein inhibit glucose uptake into chondrocytes, a mechanism for anti-osteoarthritis drugs?

Rhein has been shown to inhibit the uptake of glucose into Ehrlich Ascites tumor cells. In this paper we show that a wide range of anthraquinones related to rhein can also inhibit glucose uptake into chondrocytes, many significantly more than the parent molecule.

Pharmaceutical compounds

Pharmaceutical compounds of the formula STR1 in which R1 and R3 are each C1-4 alkyl or C1-4 alkyl-carbonyl, and R2 is carboxy, tetrazolyl, C1-4 alkyl-sulphonamido or --CR4 R5 CO2 H where R4 and R5 are each hydrogen or C1-4 alkyl; provided that when R1 and R3 are both methyl and when R1 and R3 are both methylcarbonyl, R2 is not carboxy; and salts and esters thereof.