195964-69-3

Basic information

• Product Name: 4-(2-Cyano-ethyl)-3,5-dioxo-cyclohexanecarboxylic acid ethyl ester
• CAS NO: 195964-69-3
• Molecular Weight: 237.255
• Mol File: 195964-69-3.mol

Chemical Properties

• CAS DataBase Reference: 4-(2-Cyano-ethyl)-3,5-dioxo-cyclohexanecarboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-Cyano-ethyl)-3,5-dioxo-cyclohexanecarboxylic acid ethyl ester(195964-69-3)
• EPA Substance Registry System: 4-(2-Cyano-ethyl)-3,5-dioxo-cyclohexanecarboxylic acid ethyl ester(195964-69-3)

Safety Data

• Hazardous Substances Data: 195964-69-3(Hazardous Substances Data)

Upstream product

• 1187-74-2 diethyl 2-acetylmethyl-1,4-butanedioate 
• 107-13-1 acrylonitrile 

Downstream Products

• 195964-70-6 4-(2-Cyano-ethyl)-5-oxo-cyclohex-3-enecarboxylic acid ethyl ester 

Relevant articles and documents

The first total synthesis of (±)-huperzine B

Huperzine B, a new Lycopodium alkaloid, exhibits a memory facilitating effect in mice and may be useful as an acetylcholinesterase inhibitor for the treatment of Alzheimer's disease. An efficient synthetic approach to huperzine B has been established successfully. The tetracyclic intermediate 10 is constructed by means of a tandem Michael addition and intramolecular Mannich cyclization using 8 and 9 as two components. Racemic huperzine B is obtained via a reaction sequence of 12 steps in 6.6% overall yield.