Ganglioside GM2 Sodium Salt is a complex glycosphingolipid that is a major constituent of neuronal cell membranes and the endoplasmic reticulum. It is characterized by a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage. The classification of gangliosides can be found in the work of Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.
19600-01-2
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Basic information
- Product Name: GANGLIOSIDE GM2 SODIUM SALT
- Synonyms: GANGLIOSIDE GM2;GANGLIOSIDE GM2, MONOSIALO;GANGLIOSIDE GM2 (NEUAC)SODIUM SALT;GANGLIOSIDE GM2 SODIUM SALT;GM2 NA;CER GLC GAL(NEUAC) GALNAC;MONOSIALOGANGLIOSIDE GM2;MONOSIALOGANGLIOSIDE GM2, BOVINE
- CAS NO:19600-01-2
- Molecular Formula: C68H123N3O26
- Molecular Weight: 1398.70872
- EINECS: N/A
- Product Categories: N/A
- Mol File: 19600-01-2.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: chloroform/methanol (9:1): 10 mg/mL, clear, slightly yellow
- CAS DataBase Reference: GANGLIOSIDE GM2 SODIUM SALT(CAS DataBase Reference)
- NIST Chemistry Reference: GANGLIOSIDE GM2 SODIUM SALT(19600-01-2)
- EPA Substance Registry System: GANGLIOSIDE GM2 SODIUM SALT(19600-01-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- F: 10-21
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 19600-01-2(Hazardous Substances Data)
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19600-01-2 Usage
Uses
Used in Pharmaceutical Industry:Ganglioside GM2 Sodium Salt is used as a therapeutic agent for the treatment of certain neurological disorders, such as Tay-Sachs disease and other gangliosidoses. It plays a crucial role in maintaining the integrity and function of neuronal cell membranes, which can be compromised in these conditions.
Used in Research and Development:
Ganglioside GM2 Sodium Salt is used as a research tool for studying the structure, function, and interactions of gangliosides in various biological processes. It helps researchers understand the role of these complex lipids in cell signaling, membrane trafficking, and other cellular functions.
Used in Diagnostic Applications:
Ganglioside GM2 Sodium Salt can be employed in the development of diagnostic tests for detecting and monitoring the progression of neurological disorders associated with ganglioside abnormalities. Its presence or absence in biological samples can serve as a biomarker for these conditions.
Used in Drug Delivery Systems:
Ganglioside GM2 Sodium Salt may be utilized in the development of targeted drug delivery systems, particularly for the treatment of neurological disorders. Its ability to interact with specific cell types and receptors can be exploited to enhance the delivery of therapeutic agents to the affected cells and tissues.
Biochem/physiol Actions
Minor component of cell membranes that has been shown to accumulate in Tay-Sachs disease.Check Digit Verification of cas no
The CAS Registry Mumber 19600-01-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,6,0 and 0 respectively; the second part has 2 digits, 0 and 1 respectively.Calculate Digit Verification of CAS Registry Number 19600-01:
(7*1)+(6*9)+(5*6)+(4*0)+(3*0)+(2*0)+(1*1)=92
92 % 10 = 2
So 19600-01-2 is a valid CAS Registry Number.
19600-01-2Upstream product
19600-01-2Downstream Products
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GANGLIOSIDE GM2 SODIUM SALT
