196086-05-2

Upstream product

• 171721-11-2 5-O-benzoyl-1,2-O-isopropylidene-α-L-ribofuranose 
• 4099-88-1 2,3-O-isopropylidene-L-ribofuranose 
• 76-83-5 trityl chloride 
• 196086-03-0 3-Amino-2-cyano-4-((3aR,6S,6aS)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-pyrrole-1-carboxylic acid ethyl ester 
• 196102-44-0 (E)-3-(Cyanomethyl-amino)-2-((3aR,6S,6aS)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-acrylonitrile 
• 196101-72-1 (E)-3-Dimethylamino-2-((3aR,6S,6aS)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-acrylonitrile 
• 196101-51-6 ((3aR,6S,6aS)-2,2-Dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-acetonitrile 

Downstream Products

• 196086-10-9 7-((3aR,4R,6S,6aS)-2,2-Dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-5H-pyrrolo[3,2-d]pyrimidin-4-ylamine 

Relevant academic research and scientific papers

Synthesis of L-ribofuranosyl C-nucleosides

C-Nucleosides, 4-amino-8-(β-L-ribofuranosyl)pyrazolo[1,5-α]-1,3,5-triazine (12) and 4-amino-7-( β-L-ribofuranosyl)-5H-pyrrolo[3,2-d]pyrimidine (L-9-deazaadenosine, 22), were synthesized from the key intermediate, 3 -dimethylamino-2-(2,3-O-isopropylidene-5-O-trityl-L-ribofuranosyl)acrylonitrile (8), which was prepared from L-xylose in 11 steps.