196092-88-3

Upstream product

• 128-08-5 N-Bromosuccinimide 
• 160648-53-3 O-acetyl-N-phthaloyl-L-tyrosine methyl ester 
• 39739-09-8 methyl (S)-2-(1,3-dioxoisoindolin-2-yl)-3-(4-hydroxyphenyl)propanoate 
• 1080-06-4 L-Tyr-OMe 
• 60-18-4 L-tyrosine 
• 29588-94-1 N-phthaloyl-L-tyrosine 
• 85-44-9 phthalic anhydride 

Downstream Products

• 132785-28-5 (2S,3R)-3-hydroxy-N-phthaloyltyrosine methyl ester 
• 132785-28-5 (2S,3S)-3-hydroxy-N-phthaloyltyrosine methyl ester 
• 160648-59-9 (2S,3R)-O-acetyl-3-hydroxy-N-phthaloyl-tyrosine methyl ester 
• 863871-23-2 (2S,3R)-3-methoxy-N-phthaloyl-tyrosine methyl ester 
• 863871-24-3 (2S,3S)-3-methoxy-N-phthaloyl-tyrosine methyl ester 
• 700816-79-1 (2S,3S)-2-amino-3-(4-hydroxyphenyl)-3-methoxypropanoic acid 
• 700816-76-8 (2S,3R)-β-methoxytyrosine 
• 863871-29-8 (2S,3S)-β-methoxytyrosine methyl ester 
• 863871-28-7 (2S,3R)-β-methoxytyrosine methyl ester 

Relevant academic research and scientific papers

Concise synthesis of all stereoisomers of β-methoxytyrosine and determination of the absolute configuration of the residue in callipeltin A

(Chemical Equation Presented) All stereoisomers of β-methoxytyrosine (β-OMeTyr), a stereo-undefined component of callipeltin A, were synthesized from L- and D-tyrosine. The stereochemistry of β-OMeTyr in callipeltin A was determined to be 2R,3R by an oxidative procedure and Marfey's analysis.

SYNTHESIS OF HOMOCHIRAL HYDROXY-α-AMINO ACID DERIVATIVES

Treatment of N-phthaloyl-α-amino acid methyl esters with N-bromosuccinimide, followed by reaction with silver nitrate in aqueous acetone, affords homochiral hydroxy-α-amino acid derivatives, the stereochemistry of which is predetermined by that of the starting amino acids.