1961-38-2 Usage
General Description
2-CYANO-N-(2,4-DIFLUORO-PHENYL)-ACETAMIDE is a chemical compound that belongs to the class of amides. It is formed by the reaction of 2,4-difluorobenzoyl chloride with potassium cyanide, followed by reaction with an amine. It is a white solid with a molecular formula of C10H7F2N3O, and a molecular weight of 221.18 g/mol. 2-CYANO-N-(2,4-DIFLUORO-PHENYL)-ACETAMIDE is of interest in the field of medicinal chemistry due to its potential as an antimicrobial agent. It may also have applications in the development of pharmaceuticals and agrochemicals. Additionally, it is important to handle this chemical with care and use appropriate safety measures, as it may be hazardous if not used properly.
Check Digit Verification of cas no
The CAS Registry Mumber 1961-38-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,6 and 1 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1961-38:
(6*1)+(5*9)+(4*6)+(3*1)+(2*3)+(1*8)=92
92 % 10 = 2
So 1961-38-2 is a valid CAS Registry Number.
1961-38-2Relevant articles and documents
Synthesis, cytotoxic characterization, and SAR study of imidazo[1,2-b]pyrazole-7-carboxamides
Demjén, András,Alf?ldi, Róbert,Angyal, Anikó,Gyuris, Márió,Hackler, László,Szebeni, Gábor J.,W?lfling, János,Puskás, László G.,Kanizsai, Iván
, (2018/07/13)
The synthesis and in vitro cytotoxic characteristics of new imidazo[1,2-b]pyrazole-7-carboxamides were investigated. Following a hit-to-lead optimization exploiting 2D and 3D cultures of MCF-7 human breast, 4T1 mammary gland, and HL-60 human promyelocytic leukemia cancer cell lines, a 67-membered library was constructed and the structure–activity relationship (SAR) was determined. Seven synthesized analogues exhibited sub-micromolar activities, from which compound 63 exerted the most significant potency with a remarkable HL-60 sensitivity (IC50 = 0.183 μM).
