19611-69-9Relevant academic research and scientific papers
A Pd[0]-catalyzed Ullmann cross-coupling/reductive cyclization approach to C-3 mono-alkylated oxindoles and related compounds
Banwell, Martin G.,Jones, Matthew T.,Loong, David T.J.,Lupton, David W.,Pinkerton, David M.,Ray, Jayanta K.,Willis, Anthony C.
experimental part, p. 9252 - 9262 (2011/01/12)
The Pd[0]-catalyzed Ullmann cross-coupling of o-nitrohaloarenes 1a-e with the brominated heterocycles 2a-f delivers the expected products 3a-j in good to excellent yields. The reductive cyclization of such products, as well as N-acyl derivatives 3k, l, and m, has been investigated and provided the C-3 mono-substituted oxindoles 5a-d, f, g, k, and m, the direct reduction products 4i and j or indole 5l.
