19615-22-6Relevant academic research and scientific papers
3-Acetoxyamino-2-trifluoromethylquinazolin-4(3H)one as an Aziridinating Agent for Alkenes
Atkinson, Robert S.,Coogan, Michael P.,Cornell, Clive L.
, p. 1215 - 1216 (1993)
The title compound 4, prepared by lead tetraacetate oxidation of 5, is stable at room temperature and aziridinates alkenes in better yield and higher diastereoselectivity than, e.g. the 2-ethyl compound 1; hydrazinolysis of the quinazolinone ring in 20 gives the corresponding N-aminoaziridine 21 in 64percent yield.
