196194-98-6

Basic information

• Product Name: 2-Acetamido-5-methoxy-4-nitrobenzoic Acid
• Synonyms: 2-Acetamido-5-methoxy-4-nitrobenzoic Acid;2-(Acetylamino)-5-methoxy-4-nitroBenzoic acid;Benzoic acid, 2-(acetylaMino)-5-Methoxy-4-nitro-
• CAS NO: 196194-98-6
• Molecular Formula: C₁₀H₁₀N₂O₆
• Molecular Weight: 254.197
• Product Categories: Acids and Derivatives
• Mol File: 196194-98-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 526.4°C at 760 mmHg
• Flash Point: 272.1°C
• Appearance: /
• Density: 1.487g/cm³
• Vapor Pressure: 6.59E-12mmHg at 25°C
• Refractive Index: 1.628
• CAS DataBase Reference: 2-Acetamido-5-methoxy-4-nitrobenzoic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Acetamido-5-methoxy-4-nitrobenzoic Acid(196194-98-6)
• EPA Substance Registry System: 2-Acetamido-5-methoxy-4-nitrobenzoic Acid(196194-98-6)

Safety Data

• Hazardous Substances Data: 196194-98-6(Hazardous Substances Data)

Usage

General Description

2-Acetamido-5-methoxy-4-nitrobenzoic Acid is a synthetic chemical compound that belongs to the class of nitrobenzoic acids. It is commonly used as a reagent in organic synthesis and as a building block in drug development. 2-Acetamido-5-methoxy-4-nitrobenzoic Acid has a molecular formula C10H10N2O6 and a molar mass of 258.20 g/mol. It is a white to off-white crystalline powder that is sparingly soluble in water but more soluble in organic solvents such as ethanol, methanol, and acetone. Its main functional groups include an acetamido group, a methoxy group, and a nitro group, which give it important chemical and biological properties. 2-Acetamido-5-methoxy-4-nitrobenzoic Acid is often used in the pharmaceutical industry as a starting material for the synthesis of various biologically active compounds.

InChI:InChI=1/C10H10N2O6/c1-5(13)11-7-4-8(12(16)17)9(18-2)3-6(7)10(14)15/h3-4H,1-2H3,(H,11,13)(H,14,15)

Upstream product

• 102-50-1 2-methyl-4-methoxyaniline 
• 196194-97-5 N-(4-methoxy-2-methyl-5-nitrophenyl)acetamide 
• 7487-88-9 magnesium sulfate 

Downstream Products

• 1378949-37-1 methyl 2-acetamido-4-amino-5-methoxybenzoate 
• 1378949-39-3 2-amino-5-methoxy-4-nitrobenzoic acid hydrochloride 
• 1378949-42-8 methyl 2-acetamido-4-(2-amino-5-methoxy-4-nitrobenzamido)-5-methoxybenzoate hydrochloride 
• 1378949-43-9 methyl 2-acetamido-4-(2-acetamido-5-methoxy-4-nitrobenzamido)-5-methoxybenzoate 
• 1378949-46-2 methyl 2-acetamido-5-methoxy-4-(5-methoxy-2-(3-methylbutanamido)-4-nitrobenzamido)benzoate 
• 1378949-47-3 methyl 2-acetamido-5-methoxy-4-(5-methoxy-4-nitro-2-(2-phenylacetamido)benzamido)benzoate 
• 1378949-48-4 methyl 2-acetamido-4-(2-acetamido-4-amino-5-methoxybenzamido)-5-methoxybenzoate 
• 1378949-50-8 methyl 2-acetamido-4-(2-acetamido-4-(2-amino-5-methoxy-4-nitrobenzamido)-5-methoxybenzamido)-5-methoxybenzoate hydrochloride 
• 1378949-53-1 methyl 2-acetamido-4-(2-acetamido-4-(2-acetamido-5-methoxy-4-nitrobenzamido)-5-methoxybenzamido)-5-methoxybenzoate 
• 875155-09-2 methyl 2-acetamido-5-methoxy-4-nitrobenzoate 
• 196195-05-8 N-(2-fluoro-5-methoxycarbonyloxy-4-methylphenyl)-6-methoxy-7-methoxyacetamido-4-quinazolinylamine 
• 257938-45-7 N-(2-fluoro-4-chlorophenyl)-7-amino-6-methoxy-4-quinazolinylamine 
• 196195-00-3 6-methoxy-7-nitro-3,4-dihydroquinazolin-4-one 
• 196194-99-7 2-amino-5-methoxy-4-nitrobenzoic acid 

Relevant articles and documents

Phenyl [...] compound and its preparation method, pharmaceutical composition, drug use (by machine translation)

The invention provides a phenylurea coupling quinazoline compound or a pharmaceutically acceptable salt thereof represented by formula (I), wherein R1 represents H, represents Br, Cl or F, represents -CH3, -CH2-CH3, -CH2(CH3)2 or -CF3, represents -O-CH3, -O-CH2-CH3 or -O-CH2(CH3)2, or represents -C[triple bond]CH or -C[triple bond]N; n1 is 1, 2, 3, 4 or 5; one of R2 and R3 is a group represented by formula (II); R4 represents H, represents Br, Cl or F, represents -CH3, -CH2-CH3, -CH2(CH3)2 or -CF3, represents -O-CH3, -O-CH2-CH3 or -O-CH2(CH3)2, represents -NH2, or represents -NO2; n2 is 1, 2, 3, 4 or 5; and the other one of R2 and R3 represents H, -O-CH3, -O-CH2-CH3, -O-CH2(CH3)2, or the following groups.

UREA-SUBSTITUTED AND URETHANE-SUBSTITUTED ACYLUREAS, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS

The invention relates to urea-substituted and urethane-substituted acylureas, to physiologically compatible salts thereof and to their physiologically functional derivatives. The invention thus relates to compounds of formula (I), wherein the radicals have the cited meanings. The invention also relates to the physiologically compatible salts of these compounds and to methods for the production thereof. The inventive compounds are suited for use, for example, as antidiabetics.