19621-74-0Relevant academic research and scientific papers
TOTAL SYNTHESES OF EBURNAMONINE, QUEBRACHAMINE, VINCADINE AND EPIVINCADINE
Wenkert, Ernest,Halls, Timothy D. J.,Kwart, Lawrence D.,Magnusson, Goeran,Showalter, H. D. Hollis
, p. 4017 - 4025 (1981)
Syntheses of the alkaloids eburnamonine and quebrachamine are presented in which the non-tryptamine portion of the skeleta is constructed by the β-oxycyclopropylcarboxylate preparation-fragmentation route.A similar reaction scheme is utilized for the synthesis of the alkaloids vincadine and epivincadine.
Synthesis of vinca alkaloids and related compounds part 94 [1]. Epimerization of compounds with aspidospermane and D-secoaspidospermane skeleton [section]
Kalaus, Gyoergy,Juhasz, Imre,Eles, Janos,Greiner, Istvan,Kajtar-Peredy, Maria,Brlik, Janos,Szabo, Lajos,Szantay, Csaba
, p. 245 - 251 (2007/10/03)
The individual epimerization steps of vincadifformine (1), deethylvincadifformine isomers (2,3), their synthetic intermediates (4-13) as well as that of simpler compounds with D-secoaspidospermane skeleton (1517) were studied a) in protic medium (boiling deuteroacetic acidic) and b) under reductive (with sodium borodeuteride in boiling acetic acid, or with sodium borohydride in boiling deuteroacetic acid) conditions.
