196214-24-1

Basic information

• Product Name: N-(5-hydroxypentyl)-2-nitrobenzenesulfonamide
• Synonyms: N-(5-hydroxypentyl)-2-nitrobenzenesulfonamide
• CAS NO: 196214-24-1
• Molecular Weight: 288.324
• Mol File: 196214-24-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(5-hydroxypentyl)-2-nitrobenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-hydroxypentyl)-2-nitrobenzenesulfonamide(196214-24-1)
• EPA Substance Registry System: N-(5-hydroxypentyl)-2-nitrobenzenesulfonamide(196214-24-1)

Safety Data

• Hazardous Substances Data: 196214-24-1(Hazardous Substances Data)

Upstream product

• 2508-29-4 5-hydroxypentylamine 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 

Downstream Products

• 196214-26-3 N-Benzyl-N-(5-hydroxy-pentyl)-2-nitro-benzenesulfonamide 
• 1052103-49-7 N-(2-nitrobenzenesulfonyl)-2-piperidinone 
• 196214-28-5 N-{5-[Benzyl-(2-nitro-benzenesulfonyl)-amino]-pentyl}-N-(4-methoxy-benzyl)-2,4-dinitro-benzenesulfonamide 
• 196214-35-4 N-Benzyl-N-{5-[ethyl-(4-methoxy-benzyl)-amino]-pentyl}-2-nitro-benzenesulfonamide 
• 196214-31-0 N-Benzyl-N-[5-(4-methoxy-benzylamino)-pentyl]-2-nitro-benzenesulfonamide 

Relevant articles and documents

MACROCYCLIC AMIDES ACTING AS PLASMEPSIN INHBITORS FOR THE TREATMENT OF MALARIA

The present invention relates to medicine and in particular to the treatment of malarial infections, more particularly to inhibitors of malarial aspartic proteases - plasmepsins. Even more particularly, the invention relates to macrocyclic amides and pharmaceutical compositions thereof and their use as inhibitors for plasmepsins (Plm).

2,4-Dinitrobenzenesulfonamides: A simple and practical method for the preparation of a variety of secondary amines and diamines

2,4-Dinitrobenzenesulfonamides, readily prepared from primary amines and 2,4-dinitrobenzenesulfonyl chloride, can be alkylated by the Mitsunobu reaction or by the conventional methods to give N,N-disubstituted sulfonamides in excellent yields. Since 2,4-dinitrobenzenesulfonamides can be removed without deprotecting 2-nitrobenzenesulfonamides, a wide variety of diamines could be prepared by the combined use of these protecting/activating groups.