196296-77-2Relevant academic research and scientific papers
Aminocarbene complexes of chromium in heterocyclic chemistry, XI[≠]. - Synthesis of functionalized quinolizines and homoquinolizines from N- alkynylaminocarbene complexes of chromium intramolecular C-H activation
Rudler,Parlier,Bezennine-Lafolle,Vaissermann
, p. 2825 - 2833 (2007/10/03)
N-alkynyl aminocarbene complexes 15d and e derived from piperidin-2-one, 15f and g and from azepan-2-one yield, upon thermolysis, functionalized quinolizines 16-18d,e and homoquinolizines 16-18f,g as the result of a triple-bond insertion, a carbon-hydroge
Aminocarbene Complexes of Chromium. 8. Access to the Pyrroloindole and Pyrrolochinoline Frameworks and Synthesis of Substituted Lycoranes
Bouaucheau, Cecile,Parlier, Andree,Rudler, Henri
, p. 7247 - 7259 (2007/10/03)
The use of alkynylaminocarbene complexes of chromium as starting material for the synthesis of pyrroloindole, pyrrolochinoline, and azaacenaphtylenone skeletons via cascade insertions of alkynes and CO followed by the rearrangement of zwitterionic intermediates was examined. Both the precursor complexes, synthesized from the appropriate functionalized lactams, as well as their thermolysis products were obtained in satisfactory yields and could be fully characterized. This reaction was finally applied to the synthesis of substituted lycoranes, a result which confirmed its general scope.
