196308-75-5Relevant academic research and scientific papers
USE OF 5-HT 1A? RECEPTOR ANTAGONISTS FOR THE TREATMENT OF URINARY INCONTINENCE
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, (2008/06/13)
Compounds which: (a) bind to a 5-HT1A receptor with an affinity of at least 10M, (b) bind to a 5-HT1A receptor with an affinity at least 50-fold stronger than the affinity with which the compound binds to an alpha 1-adrenergic receptor, and (c) exhibi
1,4-disubstituted piperazines
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, (2008/06/13)
Disclosed herein are novel compounds and methods for the treatment of disorders of the lower urinary tract. The novel compounds are 1,4-disubstituted piperazine derivatives. The methods comprise the administration of the novel compounds of the invention,
USE OF 5-HT1A RECEPTOR ANTAGONISTS FOR THE TREATMENT OF URINARY INCONTINENCE
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, (2008/06/13)
The present invention discloses compositions and methods for treating neuromuscular dysfunction of the lower urinary tract in mammals, including humans, using serotonin 5-HT 1A receptor antagonist compounds that exert their inhibitory effects via pre-syna
