196309-59-8

Basic information

• Product Name: 3-[4-(4-Chloro-phenoxy)-but-2-ynyloxy]-1-methyl-1H-quinolin-2-one
• Synonyms: 3-[4-(4-Chloro-phenoxy)-but-2-ynyloxy]-1-methyl-1H-quinolin-2-one
• CAS NO: 196309-59-8
• Molecular Weight: 353.805
• Mol File: 196309-59-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[4-(4-Chloro-phenoxy)-but-2-ynyloxy]-1-methyl-1H-quinolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[4-(4-Chloro-phenoxy)-but-2-ynyloxy]-1-methyl-1H-quinolin-2-one(196309-59-8)
• EPA Substance Registry System: 3-[4-(4-Chloro-phenoxy)-but-2-ynyloxy]-1-methyl-1H-quinolin-2-one(196309-59-8)

Safety Data

• Hazardous Substances Data: 196309-59-8(Hazardous Substances Data)

Upstream product

• 2058-74-4 1-methyl-1H-indole-2,3-dione 
• 4200-22-0 1-(4-chlorophenyl)oxy-4-chloro-but-2-yne 
• 172604-63-6 3-hydroxy-1-methylquinolin-2(1H)-one 

Downstream Products

• 196309-68-9 4-(4-Chloro-phenoxymethyl)-9-methyl-2H,9H-1-oxa-9-aza-phenanthren-10-one 

Relevant articles and documents

studies in sigmatropic rearrangement of 3-(4-aryloxy-but-2-ynyloxy)-1-methylquinolin-2-ones: Synthesis of 3h-pyrano[2,3-c]quinolin-5(6H)-ones and furo[2,3-c]quinol-in-4(5H)-ones

3-(4-Aryloxybut-2-ynyloxy)-1-methylquinolin-2-ones (3), in refluxing chlorobenzene, gave 1-aryloxymethyl-6-methyl-3H-pyrano[2,3-c] quinolin-5(6H)-ones (4) and / or, 1-aryloxymethyl-2,5-dimethylfuro[2,3-c]quinolin-4(5H)-ones (5). The base or the radical initiator (azoisobutyronitrile) does not seem to have any effect on the formation of the products. Substrates (3) provided only products (5) in the presence of toluene-4-sulphonic acid. All the substrates (3) studied so far underwent sigmatropic rearrangements at the 4-quinolin-3-ynyloxypropynyl function of compound (3) to give products (4) and/or (5).