196310-99-3Relevant academic research and scientific papers
The synthesis of antioxidants showing selective affinity for low density lipoproteins
Brown, David W.,Mahon, Mary F.,Ninan, Aleyamma,Sainsbury, Malcolm
, p. 2329 - 2336 (2007/10/03)
The syntheses of some novel indolinosteroids, indolinodecalins and spiro tetrahydroquinolinopiperidines are described. These compounds act as chain-breaking antioxidants and in some cases show very selective binding to LDL particles in human plasma. Aspects of the stereoselectivity in the Fischer indolisation of three common steroidal ketones and the reduction of the resultant indoles to indolines are considered.
