19637-92-4

Upstream product

• 74332-24-4 C₁₉H₂₅N₂O⁽¹⁺⁾*CH₃O₃S^(1-) 
• 74332-24-4 C₁₉H₂₅N₂O⁽¹⁺⁾*CH₃O₃S^(1-) 
• 74332-24-4 C₁₉H₂₅N₂O⁽¹⁺⁾*CH₃O₃S^(1-) 
• 74332-24-4 C₁₉H₂₅N₂O⁽¹⁺⁾*CH₃O₃S^(1-) 
• 74332-24-4 C₁₉H₂₅N₂O⁽¹⁺⁾*CH₃O₃S^(1-) 

Downstream Products

• 1674-01-7 (+)-cleavamine 

Relevant academic research and scientific papers

CHIRALITY CONTROL BY KINETIC PROTONATION: ENANTIOSELECTIVE SYNTHESES OF (+)-VELBANAMINE, (-)-ISOVELBANAMINE, AND (+)-CLEAVAMINE

Optimal conditions for inversion of chirality at 2-position of the 2-alkyllactone(5) have been established.By utilizing the inversion method developed, three indole alkaloids, (+)-velbanamine(16), (-)-isovelbanamine(17), and (+)-cleavamine(18), have been synthesized from the chiral lactone(1) which has been previously used for the syntheses of the enantiomers of these alkaloids.

ENANTIOSELECTIVE SYNTHESIS OF (-)-VELBANAMINE AND (+)-ISOVELBANAMINE USING L-GLUTAMIC ACID AS CHIRAL TEMPLATE

Enantioselective synthesis of (-)-velbanamine (1) and (+)-isovelbanamine (2) has been accomplished using L-glutamic acid as chiral template.