196409-50-4

Upstream product

• 196409-39-9 (S)-2-(tert-Butyl-dimethyl-silanyloxy)-N-methoxy-N-methyl-3-((R)-toluene-4-sulfinyl)-propionamide 
• 1730-25-2 allylmagnesium bromide 
• 1519-39-7 (R)-methyl p-tolyl sulfoxide 
• 196409-37-7 (R)-N-methoxy-N-methyl-2-oxo-3-(p-tolylsulfinyl)propanamide 
• 196409-38-8 (2S)-2-hydroxy-N-methoxy-N-methyl-3-[(R)-p-tolylsulfinyl]propanamide 

Downstream Products

• 852637-92-4 (2S,4R,5R)-4-Allyl-2-(4-methoxy-phenyl)-[1,3]dioxan-5-ol 
• 852637-91-3 [(2S,4R,5R)-4-Allyl-2-(4-methoxy-phenyl)-[1,3]dioxan-5-yloxy]-tert-butyl-dimethyl-silane 
• 852637-88-8 (2S,3R)-2-(tert-butyldimethylsilyloxy)-3-[(2-methoxyethoxy)methoxy]-1-[(R)-p-tolylsulfinyl]hex-5-ene 
• 852637-89-9 acetic acid 2-(tert-butyl-dimethyl-silanyloxy)-3-(2-methoxy-ethoxymethoxy)-1-p-tolylsulfanyl-hex-5-enyl ester 
• 221638-05-7 (2S,3S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-((R)-toluene-4-sulfinyl)-hex-5-en-3-ol 
• 221638-09-1 (2S,3R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-((R)-toluene-4-sulfinyl)-hex-5-en-3-ol 

Relevant academic research and scientific papers

Enantioselective sulfoxide-directed preparation of 1,2-diols from oxalic compounds: Formal synthesis of the 10-membered lactone core of ascidiatrienolides and didemnilactones

The synthesis of diene 17, which is available in both possible absolute configurations is described. This diene constitutes the key intermediate of a previous synthesis of the 10-membered lactone core of the marine natural products ascidiatrienolides and

Stereoselective sulfoxide directed reduction of 1,2-diketo-derivatives to enantiomerically pure syn and anti 1,2-diols

A new route to enantiopure syn and anti 1,2-diols is described from oxalyl-di-(N-methyl-N-methoxyamide) via the corresponding β-ketosulfoxide. This is the first report of the stereoselective reduction of a γ-keto-β-hydroxysulfoxide.