19654-24-1Relevant academic research and scientific papers
Optical Control of the GTP Affinity of K-Ras(G12C) by a Photoswitchable Inhibitor
Ge, Zhihua,Yang, Zhuojin,Liang, Jingshi,Dong, Duoling,Zhu, Mingyan
, p. 2916 - 2920 (2019)
Photocontrol of protein activity is an emerging field in biomedicine. For optical control of a mutant small GTPase K-Ras(G12C), we developed small-molecule inhibitors with photoswitchable efficacy, where one configuration binds the target protein and exer
