1966-16-1

Usage

Uses

Used in Pharmaceutical Industry:
(5-CHLORO-2-NITROPHENYL)HYDRAZINE is used as a building block for the synthesis of various pharmaceuticals due to its versatile chemical structure. Its ability to form intermediates makes it a valuable component in the development of new drugs and medications.
Used in Dye Production:
In the dye industry, (5-CHLORO-2-NITROPHENYL)HYDRAZINE is used as a key compound in the production of different types of dyes. Its chemical properties contribute to the color and stability of the dyes, making it an essential component in this application.
Used in Chemical Analysis:
As a reagent, (5-CHLORO-2-NITROPHENYL)HYDRAZINE is employed in chemical analysis to facilitate various reactions and help identify or quantify specific substances. Its unique properties make it suitable for use in analytical processes.
Used in Organic Synthesis:
(5-CHLORO-2-NITROPHENYL)HYDRAZINE has potential applications in the field of organic synthesis, where it can be used to create a range of organic compounds. Its nitrogen-nitrogen double bond allows for various synthetic pathways, expanding the possibilities for new compound development.
Safety Precautions:
Due to its moderate toxicity, (5-CHLORO-2-NITROPHENYL)HYDRAZINE should be handled with care. Proper safety measures, including the use of personal protective equipment and adherence to safety protocols, should be followed to minimize the risk of exposure and ensure the safety of those working with (5-CHLORO-2-NITROPHENYL)HYDRAZINE.

Upstream product

• 1635-61-6 5-chloro-2-nitroaniline 
• 610-40-2 3,4-dinitro-chlorobenzene 
• 64-17-5 ethanol 
• 7803-57-8 hydrazine hydrate 
• 121-73-3 3-Nitrochlorobenzene 

Downstream Products

• 75132-65-9 acetic acid-[N'-(5-chloro-2-nitro-phenyl)-hydrazide] 
• 94724-86-4 3-(5-chloro-2-nitro-phenylhydrazono)-butyric acid ethyl ester 
• 101935-90-4 benzophenone-(5-chloro-2-nitro-phenylhydrazone) 
• 78753-36-3 3-[(5-Chloro-2-nitro-phenyl)-hydrazono]-3-phenyl-propionic acid ethyl ester 

Relevant academic research and scientific papers

HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE

The present invention relates to compounds and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.

HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE

The present invention relates to compounds and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.

Benzo[4,5]imidazo[2,1-a]phthalazines: I. Substituted o- nitrophenylhydrazines in the synthesis of phthalazin-1(2H)-ones

Efficient cyclization procedure was developed for 2-nitro-, 2,4-dinitro-, 2-nitro-5-chloro-, and 4,5-dichloro-2-nitrophenylhydrazines with 2-acylbenzoic acids by heating the reagents in a mixture of of concentrated sulfuric acid and ethanol. A series of n

Competitive Cyclisations of Singlet and Triplet Nitrenes. Part 8. The 1-(2-Nitrenophenyl)pyrazoles and Related Systems

The title nitrenes, derived by nitro-group deoxygenation with triethyl phosphite or by thermolysis or photolysis of the corresponding azide, have been studied.The effect of substituents (Cl, Br, OMe, NMe2, Me, CF3, and NO2) both meta and para to the nitrene has been examined as a determinant of the preferred mode of cyclisation to either a pyrazolobenzotriazole or a pyrazoloquinoxaline.Similarly, the role of solvents, sensitisers, and quenchers has been studied.Routes to the isomeric 1- and 2-(2-nitrophenyl)-4,5,6,7-tetrahydroindazoles have been defined and the literature corrected by studing the nitrene-mediated cyclisation of these products.The chemistry of the analogous 1-(2-carbenophenyl)- and the 1-(2-nitrenosulphonylphenyl)-3,5-dimethylpyrazoles has also been examined, the former giving 2-(3,5-dimethylpyrazol-1-yl)-benzaldazine and -benzyl alcohol while the latter gave products of intramolecular nitrene attack (a pyrazolobenzothiatriazine) and intermolecular reaction.Rationalisations for all the reaction pathways have been advanced.