196603-47-1Relevant articles and documents
4-ANILINOQUINAZOLINE DERIVATIVES
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, (2008/06/13)
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196603-47-1
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Basic information
- Product Name: ZM 306416 hydrochloride
- Synonyms:
- CAS NO:196603-47-1
- Molecular Formula:
- Molecular Weight: 370.21
- EINECS: N/A
- Product Categories: N/A
- Mol File: 196603-47-1.mol
- Article Data: 2
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: ZM 306416 hydrochloride(CAS DataBase Reference)
- NIST Chemistry Reference: ZM 306416 hydrochloride(196603-47-1)
- EPA Substance Registry System: ZM 306416 hydrochloride(196603-47-1)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 196603-47-1(Hazardous Substances Data)
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196603-47-1 Usage
Description
ZM 306416 hydrochloride, also known as ZM-306416, is a VEGF receptor tyrosine kinase inhibitor with selectivity over FGFR-1. It is a pharmaceutical compound that targets the tyrosine kinase RTK signaling pathway, which plays a crucial role in cancer development and progression. With its ability to inhibit VEGF receptor tyrosine kinase, ZM 306416 hydrochloride has demonstrated potential as an anti-tumor and anti-metastatic agent.Uses
Used in Pharmaceutical Industry:ZM 306416 hydrochloride is used as an anti-cancer agent for its ability to inhibit the tyrosine kinase RTK signaling pathway, which is involved in tumor growth and metastasis. Its selectivity over FGFR-1 makes it a promising candidate for targeted cancer therapies.
ZM 306416 hydrochloride is used as an anti-tumor agent for its potential to inhibit the growth of cancer cells by targeting the VEGF receptor tyrosine kinase, a key player in tumor angiogenesis.
ZM 306416 hydrochloride is used as an anti-metastatic agent for its ability to prevent the spread of cancer cells to other parts of the body by inhibiting the VEGF receptor tyrosine kinase, which is crucial for the formation of new blood vessels that support tumor growth and metastasis.
References
1) Hennequin et al. (1999) Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors. J. Med. Chem. 42 5369Check Digit Verification of cas no
The CAS Registry Mumber 196603-47-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,6,6,0 and 3 respectively; the second part has 2 digits, 4 and 7 respectively.Calculate Digit Verification of CAS Registry Number 196603-47:
(8*1)+(7*9)+(6*6)+(5*6)+(4*0)+(3*3)+(2*4)+(1*7)=161
161 % 10 = 1
So 196603-47-1 is a valid CAS Registry Number.
196603-47-1Upstream product
196603-47-1Downstream Products
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ZM 306416 hydrochloride
