196695-49-5Relevant articles and documents
Combinations of protein farnesyltransferase and HMG CoA reductase inhibitors and their use to treat cancer
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, (2008/06/13)
Novel combinations of inhibitors of protein farnesyltransferase enzymes and HMG CoA reductases enzymes are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in preventing or treating cancer, restenosis, psoriasis, endometriosis, atherosclerosis, or viral infections.
C-terminal modifications of histidyl-N-benzylglycinamides to give improved inhibition of Ras farnesyltransferase, cellular activity, and anticancer activity in mice.
McNamara,Dobrusin,Leonard,Shuler,Kaltenbronn,Quin 3rd.,Bur,Thomas,Doherty,Scholten,Zimmerman,Gibbs,Gowan,Latash,Leopold,Przybranowski,Sebolt-Leopold
, p. 3319 - 3322 (2007/10/03)
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