196704-18-4Relevant academic research and scientific papers
Structure-binding relation of philanthotoxins from nicotinic acetylcholine receptor binding assay
Nakanishi, Koji,Huang, Xuefei,Jiang, Hong,Ying, Liu,Fang, Kan,Huang, Danwen,Choi, Seok-Ki,Katz, Elizabeth,Eldefrawi, Mohyee
, p. 1969 - 1988 (1997)
Philanthotoxins are noncompetitive inhibitors of the nicotinic acetylcholine receptor and the various glutamate receptors. Analogues carrying photoaffinity labels, fluorine atoms for solid-state NMR studies of ligand/receptor interaction, and large head g
Synthesis and pharmacological activity of philanthotoxin-343 analogs: Antagonists of ionotropic glutamate receptors
Huang, Danwen,Jiang, Hong,Nakanishi, Koji,Usherwood
, p. 12391 - 12404 (2007/10/03)
The synthesis of two classes of Philanthotoxin-343 analogs is described. Quantitative information on the antagonism of quisqualate-sensitive ionotropic glutamate receptors of insect muscle by these compounds is presented.
