196711-63-4Relevant academic research and scientific papers
17-imidazolyl, pyrazolyl, and isoxazolyl androstene derivatives. Novel steroidal inhibitors of human cytochrome C17,20-lyase (P45017α)
Ling, Yang-Zhi,Li, Ji-Song,Liu, Yang,Kato, Katsuya,Klus, Gregory T.,Brodie, Angela
, p. 3297 - 3304 (1997)
We recently described a number of inhibitors of P45017α, the key enzyme of androgen biosynthesis. Here, we report the synthesis and activity of novel 17-imidazolyl, pyrazolyl, and isoxazolyl androstene derivatives as potential agents for the tr
