19673-37-1

Basic information

• Product Name: 1-[(4-Methylphenyl)sulfonyl]-1H-1-benzazepin-3(2H)-one
• Synonyms: 1-[(4-Methylphenyl)sulfonyl]-1H-1-benzazepin-3(2H)-one
• CAS NO: 19673-37-1
• Molecular Formula: C₁₇H₁₅NO₃S
• Molecular Weight: 313.37
• Mol File: 19673-37-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-[(4-Methylphenyl)sulfonyl]-1H-1-benzazepin-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(4-Methylphenyl)sulfonyl]-1H-1-benzazepin-3(2H)-one(19673-37-1)
• EPA Substance Registry System: 1-[(4-Methylphenyl)sulfonyl]-1H-1-benzazepin-3(2H)-one(19673-37-1)

Safety Data

• Hazardous Substances Data: 19673-37-1(Hazardous Substances Data)

Upstream product

• 6590-65-4 N-(2-Formyl-phenyl)-4-methyl-benzenesulfonamide 
• 1224713-12-5 N-(2-formylphenyl)-4-methyl-N-(prop-2-yn-1-yl)benzenesulfonamide 

Downstream Products

• 19673-44-0 4,5-dibromo-1-(toluene-4-sulfonyl)-1,2,4,5-tetrahydro-spiro[benzo[b]azepine-3,2'-[1,3]dioxolane] 

Relevant articles and documents

Synthesis of (Z)-1,2-dihydro-1-tosylbenzo[b]azepin-3-ones by two-step, one-pot gold-catalyzed tandem heterocyclization/Petasis-Ferrier rearrangement of 2-(N-(prop-2-ynyl)-N-tosylamino)benzaldehydes

A two-step, one-pot synthetic method that relies on gold(I)-catalyzed tandem heterocyclization/Petasis-Ferrier rearrangement and Br?nsted acid-assisted debenzoxylation of 2-(N-(prop-2-ynyl)-N-tosylamino)benzaldehydes to prepare (Z)-1,2-dihydro-1-tosylbenzo[b]azepin-3-ones efficiently is reported. The reactions proceed rapidly under mild and operationally straightforward conditions for a wide variety of aldehyde substrates containing electron-withdrawing, electron-donating, and sterically demanding functional groups and afforded the corresponding benzo-fused azaheterocyclic products in moderate to excellent yields.