196794-86-2Relevant academic research and scientific papers
Design, Synthesis, and Biological Evaluation of Thio-Containing Compounds with Serum HDL-Cholesterol-Elevating Properties
Elokdah, Hassan,Sulkowski, Theodore S.,Abou-Gharbia, Magid,Butera, John A.,Chai, Sie-Yearl,McFarlane, Geraldine R.,McKean, Mar-Lee,Babiak, John L.,Adelman, Steven J.,Quinet, Elaine M.
, p. 681 - 695 (2007/10/03)
A novel series of substituted sulfanyldihydroimidazolones (1) that modulates high-density lipoprotein cholesterol (HDL-C) has been reported to have HDL-elevating properties in several animal models. Concerns about the chemical and metabolic stability of 1
2-thioxo-tetrahydropyrimidin-4-one derivatives
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, (2008/06/13)
This invention relates to the use of 2-thioxotetrahydropyrimidin-4-one derivatives to increase HDL cholesterol concentration and as therapeutic compositions for treating atherosclerotic conditions such as dyslipoproteinemias and coronary heart disease. Th
