196795-22-9

Upstream product

• 181207-92-1 ((2S,3R)-3-Benzenesulfonyl-oxiranylmethoxy)-tert-butyl-diphenyl-silane 
• 196795-21-8 Trifluoro-methanesulfonic acid (4aS,6R,7S,9aR)-7-triethylsilanyloxy-octahydro-1,5-dioxa-benzocyclohepten-6-ylmethyl ester 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 181378-20-1 (2S,3R)-3-Benzenesulfonyl-oxirane-2-carbaldehyde 
• 196795-13-8 (S)-1-((2S,3R)-3-Benzenesulfonyl-oxiranyl)-ethane-1,2-diol 
• 181208-08-2 (2R,4aR,8aS)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-hexahydro-pyrano[3,2-b]pyran-3-one 
• 196795-20-7 (4aS,6R,7S,9aR)-6-Hydroxymethyl-octahydro-1,5-dioxa-benzocyclohepten-7-ol 
• 196795-19-4 (4aS,6R,9aR)-6-Hydroxymethyl-hexahydro-1,5-dioxa-benzocyclohepten-7-one 
• 196795-17-2 (4aS,6R,9aR)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-hexahydro-1,5-dioxa-benzocyclohepten-7-one 

Downstream Products

• 196795-34-3 (4aS,6R,7S,9aR)-6-[(2R,3S)-2-Benzenesulfonyl-3-(tert-butyl-diphenyl-silanyloxymethyl)-oxiranylmethyl]-octahydro-1,5-dioxa-benzocyclohepten-7-ol 
• 196795-26-3 (4aS,5aR,9R,10aS,12aR)-9-(tert-Butyl-diphenyl-silanyloxymethyl)-decahydro-1,5,10-trioxa-benzo[b]heptalen-8-one 
• 196795-23-0 (2R,4aR,5aS,9aR,11aS)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-decahydro-1,5,9-trioxa-dibenzo[a,d]cyclohepten-3-one 
• 196795-24-1 (2R,3S,4aR,5aS,9aR,11aS)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-dodecahydro-1,5,9-trioxa-dibenzo[a,d]cyclohepten-3-ol 

Relevant academic research and scientific papers

Stereoselective synthesis of the 6,7,6- and 6,7,7-ring systems of polycyclic ethers by 6-endo cyclization and ring expansion

A new strategy for the stereoselective synthesis of the trans-fused seven-membered cyclic ethers corresponding to subunits of brevetoxin B and hemibrevetoxin B has been developed. The strategy involves alkylation of an oxiranyl anion and B-endo cyclization followed by one-carbon homologation of a tetrahydropyran to an oxepane using trimethylsilyldiazomethane.