196808-79-4

Basic information

• Product Name: Fmoc-D-2-Me-Trp
• Synonyms: Fmoc-D-2-Me-Trp;(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-methyl-1H-indol-3-yl)propanoic acid;-3-(2-methyl-1H-indol-3-yl);(9H-Fluoren-9-yl)MethOxy]Carbonyl D-Trp(2-Me)-OH;(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(2-methyl-1H-indol-3-yl)propanoic acid;Fmoc-D-2-methylTryptophan
• CAS NO: 196808-79-4
• Molecular Formula: C27H24N2O4
• Molecular Weight: 440.49046
• Product Categories: Unusual Amino Acids
• Mol File: 196808-79-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 716.2±60.0 °C(Predicted)
• Appearance: /
• Density: 1.326±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 3.78±0.10(Predicted)
• CAS DataBase Reference: Fmoc-D-2-Me-Trp(CAS DataBase Reference)
• NIST Chemistry Reference: Fmoc-D-2-Me-Trp(196808-79-4)
• EPA Substance Registry System: Fmoc-D-2-Me-Trp(196808-79-4)

Safety Data

• Hazardous Substances Data: 196808-79-4(Hazardous Substances Data)

Usage

Description

Fmoc-D-2-Me-Trp is a chemical compound that features an N-terminal fluorenylmethyloxycarbonyl (Fmoc) protecting group, a D-form of 2-methyltryptophan (2-Me-Trp), and a functional group at the 2 position. Fmoc-D-2-Me-Trp is integral in peptide synthesis and serves as a building block for the creation of innovative peptide-based drugs and materials. The Fmoc group shields the amine group of the amino acid, while the D-2-Me-Trp group endows the resulting peptide with distinctive structural and functional attributes. These attributes may include heightened stability, altered pharmacokinetics, and augmented biological activity, making Fmoc-D-2-Me-Trp a vital component in the advancement of peptides with superior therapeutic capabilities.

Uses

Used in Pharmaceutical Industry:
Fmoc-D-2-Me-Trp is used as a building block for the synthesis of novel peptide-based drugs, leveraging its unique structural and functional properties to enhance the stability, pharmacokinetics, and biological activity of the resulting peptides. This contributes to the development of peptides with improved therapeutic potential.
Used in Peptide Synthesis:
Fmoc-D-2-Me-Trp is utilized as a key component in the synthesis of peptides, where the Fmoc group provides protection for the amine group of the amino acid, facilitating the controlled assembly of peptide sequences. The incorporation of D-2-Me-Trp into peptides can lead to modifications in their properties, such as increased stability and enhanced biological activity, which are crucial for the effectiveness of peptide-based therapeutics.
Used in Drug Development Research:
Fmoc-D-2-Me-Trp is employed as a research tool in drug development, allowing scientists to explore the effects of its unique structural features on peptide behavior. This can lead to a better understanding of peptide-drug interactions and the optimization of peptide therapeutics for various medical applications.