196930-46-8

Basic information

• Product Name: R-2-PHENYL-THIAZOLIDINE-4-CARBOXYLIC ACID
• Synonyms: (4R)-2-phenyl-1,3-thiazolidine-4-carboxylic acid
• CAS NO: 196930-46-8
• Molecular Formula: C₁₀H₁₁NO₂S
• Molecular Weight: 209.26
• Mol File: 196930-46-8.mol
• Article Data: 37

Chemical Properties

• Melting Point: 155 °C
• Boiling Point: 433.6±45.0 °C(Predicted)
• Appearance: /
• Density: 1.302±0.06 g/cm3(Predicted)
• PKA: 1.98±0.40(Predicted)
• CAS DataBase Reference: R-2-PHENYL-THIAZOLIDINE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: R-2-PHENYL-THIAZOLIDINE-4-CARBOXYLIC ACID(196930-46-8)
• EPA Substance Registry System: R-2-PHENYL-THIAZOLIDINE-4-CARBOXYLIC ACID(196930-46-8)

Safety Data

• Hazardous Substances Data: 196930-46-8(Hazardous Substances Data)

Upstream product

• 52-89-1 l-cysteine hydrochloride 
• 100-52-7 benzaldehyde 
• 52-90-4 L-Cysteine 
• 170227-63-1 N,N-dimethyl-2-thiohistidine 
• 921-01-7 D-cysteine 
• 58166-38-4 2,2-dimethyl-thiazolidine-4(R)-carboxylic acid 

Downstream Products

• 240429-81-6 (R,R')-N,N'-dibenzylcystinol 
• 69739-21-5 (2R,4R)-N-acetyl-2-phenyl-4-carboxy-1,3-thiazolidine 
• 69739-24-8 (2S,4R)-N-acetyl-2-phenyl-1,3-thiazolidine-4-carboxylic acid 
• 777067-59-1 (2R,4R)-N-ethoxyoxalyl-2-phenylthiazolidine-4-carboxylic acid 
• 473910-45-1 (2R,4R)-N-(p-methoxybenzoyl)-2-phenylthiazolidine-4-carboxylic acid 
• 473910-46-2 (2S,4R)-N-(p-methoxybenzoyl)-2-phenylthiazolidine-4-carboxylic acid 
• 137525-27-0 (2S,4R)-N-benzoyl-2-phenylthiazolidine-4-carboxylic acid 
• 158446-64-1 dimethyl (3R)-5-methyl-3-phenyl-3,4-dihydro-1H-pyrrolo[1,2-a]thiazole-6,7-dicarboxylate 
• 158446-52-7 (2R,4R)-3-(tert-butoxycarbonyl)-2-phenylthiazolidine-4-carboxylic acid 
• 161153-14-6 (2R,4R)-3-(Ethoxycarbonyl)-2-phenyl-1,3-thiazolidine-4-carboxylic acid 
• 198991-76-3 methyl (4R)-2-phenylthiazolidine-4-carboxylate 

Relevant articles and documents

Discovery of cysteine and its derivatives as novel antiviral and antifungal agents

Based on the structure of the natural product cysteine, a series of thiazolidine-4-carboxylic acids were designed and synthesized. All target compounds bearing thiazolidine-4-carboxylic acid were characterized by1 H-NMR,13 C-NMR, and

GLUCOSE-SENSITIVE PEPTIDE HORMONES

The present invention relates to a conjugate of the formula P-L-I, wherein P is a peptide hormone effecting the metabolism of carbohydrates in vivo, L is a hydrolysable linker molecule consisting of Lp and Lj, and I is a molecule capable of inhibiting the effect of the peptide hormone P on the metabolism of carbohydrates in vivo. Under in vivo conditions, the conjugate is the major compound. When the concentration of glucose increases in v/vo,the concentration of the peptide hormone effecting the metabolism of carbohydrates in vivo also increases.

Thiazolidine chemistry revisited: A fast, efficient and stable click-type reaction at physiological pH

We describe the fast reaction kinetics between 1,2-aminothiols and aldehydes. Under physiological conditions such a click-type reaction afforded a thiazolidine product that remains stable and did not require any catalyst. This type of bioorthogonal reacti