196935-03-2

Basic information

• Product Name: 2-CHLORO-N-(4-CHLORO-3-NITROPHENYL)ACETAMIDE
• Synonyms: 2-CHLORO-N-(4-CHLORO-3-NITROPHENYL)ACETAMIDE;2-chloro-N-(4-chloro-3-nitrophenyl)acetamide(SALTDATA: FREE);T0511-5061;ZINC02530992
• CAS NO: 196935-03-2
• Molecular Formula: C8H6Cl2N2O3
• Molecular Weight: 249.05
• Mol File: 196935-03-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 434.7°C at 760 mmHg
• Flash Point: 216.7°C
• Appearance: /
• Density: 1.579g/cm³
• Vapor Pressure: 9.28E-08mmHg at 25°C
• Refractive Index: 1.639
• CAS DataBase Reference: 2-CHLORO-N-(4-CHLORO-3-NITROPHENYL)ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-N-(4-CHLORO-3-NITROPHENYL)ACETAMIDE(196935-03-2)
• EPA Substance Registry System: 2-CHLORO-N-(4-CHLORO-3-NITROPHENYL)ACETAMIDE(196935-03-2)

Safety Data

• Hazardous Substances Data: 196935-03-2(Hazardous Substances Data)

Usage

General Description

2-CHLORO-N-(4-CHLORO-3-NITROPHENYL)ACETAMIDE is a chemical compound that consists of two chlorine atoms, a nitro group, and an acetamide group attached to a phenyl ring. It is primarily used as an intermediate in the synthesis of other organic compounds and pharmaceuticals. This chemical has potential applications in the field of medicine as a building block for creating new drugs and treatments. Its specific properties and reactivity make it valuable for use in various chemical reactions and processes in the pharmaceutical and chemical industries.

InChI:InChI=1/C8H6Cl2N2O3/c9-4-8(13)11-5-1-2-6(10)7(3-5)12(14)15/h1-3H,4H2,(H,11,13)

Upstream product

• 635-22-3 4-Chloro-3-nitroaniline 
• 79-04-9 chloroacetyl chloride 

Relevant articles and documents

Design, synthesis, antibacterial and quorum quenching studies of 1,2,5-trisubstituted 1,2,4-triazoles

Abstract: In view of discovering novel bioactive molecules, 1-phenyl-1H-2-(1-aryl-5-methyl-1H-1,2,3-triazol-4-yl)-3-(N-aryl-carbamoylmethylthio)-1,2,4-triazoles (8a–n) were designed and synthesized in good yield. Preliminary antibacterial activity was tested against Chromobacterium violaceum and Xanthomonas campestris pv. Campestris (Xcc). Out of 14 derivatives, compound 8g selectively possessed antibacterial activity against C. violaceum. Further derivatives that possessed an electron-withdrawing group and halogen atoms in N-phenylacetamide moiety were moderately active against Xcc (plant pathogen). After observing the reduction of violacein production through plate assay, compounds 8a, 8c, 8h, 8i and 8m were subjected to quantification of quorum sensing inhibition. Compounds with the electron-withdrawing group in N-phenylacetamide moiety showed admirable activity with > 80% inhibition of violacein. Mainly compound 8c which was inactive against the growth of bacteria were identified as excellent QSI which could be a lead compound for further development. Graphic abstract: One of the best approaches to acquire anti-virulence strategies and new direction for the discovery of antibacterial drugs[Figure not available: see fulltext.]

Combined structure- and ligand-based virtual screening aiding discovery of selenoglycolicamides as potential multitarget agents against Leishmania species

Leishmaniasis is a neglected disease that does not have adequate treatment. We created a database with 30 selenoglycolicamides and evaluated their potential anti-Leishmanial activity (L. amazonensis and L. donovani) through ligand- and structure-based vir

Activities of 2-carboxanilido 3-hydroxybenzo[b]thiophens against molluscs Biomphalaria

The title compounds are shown to be nearly as active against molluscs as Niclosamide when they are either dihalogenated or monohalogenated and mononitrated on the benzene ring.