197015-36-4Relevant academic research and scientific papers
4-benzylaminobenzenesulfonamide derivative and preparation and application thereof
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, (2020/08/30)
The invention provides a 4-benzylaminobenzenesulfonamide derivative represented by a formula (I) or a pharmaceutically acceptable salt, a solvate or a metabolite thereof. In the formula (I), R1, R2, R3, R4, R5 and R6 are defined in the specification. The
A Novel Palladium-Mediated Cascade Reaction Triggered by Strain Release of the Cyclobutane System. A New General Route to Benzo- and Naphthohydrindans
Nemoto, Hideo,Miyata, Junji,Yoshida, Masahiro,Raku, Naomi,Fukumoto, Keiichiro
, p. 7850 - 7857 (2007/10/03)
A novel palladium-mediated cascade reaction was reported.By this procedure, the olefinic cyclobutanols 17, 24, and 31; 41; 37; and 45 afforded the benzo- and naphthohydrindans (46-49, 50-53, 54-57, and 58-61) respectively in one operation in the ratios depending on the mediators and solvents employed.This provides a novel and efficient synthesis of biologically important A-nor and C11-alkylated steroids.
