19721-22-3

Basic information

• Product Name: 3-MERCAPTO-1-PROPANOL
• Synonyms: 3-MERCAPTO-1-PROPANOL;Mercaptopropanol;3-MERCAPTO-1-PROPANOL 96+%;3-MERCAPTO-1-PROPANOL FEMA NO.--------;Mercapto-1-propanol;3-Mercapto-1-propanol, 97+%;3-Mercapto-1-propanol,3-Mercaptopropanol;3-Mercaptopropan-1-ol
• CAS NO: 19721-22-3
• Molecular Formula: C₃H₈OS
• Molecular Weight: 92.16
• EINECS: 264-572-5
• Product Categories: Self Assembly&Contact Printing;Self-Assembly Materials;Sulfur Compounds;Thiols/Mercaptans;ThiolsOrganic Building Blocks;Building Blocks;Chemical Synthesis;Contact Printing;Functional Thiols;Materials Science;Micro/NanoElectronics;Organic Building Blocks;Self Assembly &Self-Assembly Materials;Sulfur Compounds;Thiols
• Mol File: 19721-22-3.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 81-82 °C10 mm Hg(lit.)
• Flash Point: 185 °F
• Appearance: Clear colorless/Liquid
• Density: 1.067 g/mL at 20 °C(lit.)
• Vapor Pressure: 0.188mmHg at 25°C
• Refractive Index: n20/D 1.495(lit.)
• PKA: 10.05±0.10(Predicted)
• BRN: 1731082
• CAS DataBase Reference: 3-MERCAPTO-1-PROPANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-MERCAPTO-1-PROPANOL(19721-22-3)
• EPA Substance Registry System: 3-MERCAPTO-1-PROPANOL(19721-22-3)

Safety Data

• Hazard Codes: T
• Statements: 24/25
• Safety Statements: 28-36/37-45
• RIDADR: UN 2810 6.1/PG 3
• WGK Germany: 3
• RTECS: UB7630000
• F: 13
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 19721-22-3(Hazardous Substances Data)

Usage

Description

3-Mercapto-1-propanol, also known as 3-MPA, is a clear colorless liquid with a thiol functional group. It is an organic compound that possesses unique chemical properties, making it a versatile building block in various applications across different industries.

Uses

Used in Chemical Synthesis:
3-Mercapto-1-propanol is used as a traceless linker for the chemical and enzymatic synthesis of oligosaccharides. Its thiol end facilitates the formation of disulfide bonds, which are crucial in the construction of complex carbohydrate structures.
Used in Surface Modification:
3-Mercapto-1-propanol is employed to produce hydrophilic self-assembled monolayers (SAMs) on various surfaces. These SAMs are essential in modifying the surface properties of materials for applications such as sensors, catalysts, and coatings.
Used in DNA Detection Systems:
3-Mercapto-1-propanol has been reported to be used as a label-free capacitive DNA detection system due to its terminating thiol end. This property allows for the selective binding and detection of DNA molecules without the need for additional labels or markers, making the detection process more efficient and reliable.

InChI:InChI=1/C3H8OS/c4-2-1-3-5/h4-5H,1-3H2

Upstream product

• 30453-21-5 3-[(3-hydroxypropyl)disulfanyl]-1-propanol 
• 115051-66-6 S-acetyl-3-thiopropyl alcohol 
• 75-56-9 methyloxirane 
• 627-30-5 1-chloro-3-hydroxypropane 
• 7664-93-9 sulfuric acid 
• 627-18-9 1-bromo-3-propanol 
• 2986-30-3 S-(3-hydroxy-propyl)-isothiourea 
• 5466-06-8 3-mercaptopropionic acid ethyl ester 
• 13095-73-3 4-mercaptobutyric acid 
• 503-30-0 trimethylene oxide 
• 107-96-0 3-mercaptopropionic acid 
• 107-18-6 allyl alcohol 

Downstream Products

• 26902-03-4 3-(benzylthio)propan-1-ol 
• 40096-07-9 Benzyl-3-hydroxypropyl-tetrasulfid 
• 66909-06-6 1-(γ-Hydroxypropylthio)-2,4,6-trinitrobenzol 
• 857894-88-3 (Z)-S-(3-hydroxypropyl) phenylacetothiohydroximate 
• 100360-56-3 3-(tritylthio)propan-1-ol 
• 1283167-23-6 C₂₁H₂₂N₂OS 
• 1283167-24-7 C₂₁H₂₂N₂O₃S 
• 915694-24-5 tert-butyl 3-mercaptopropyl malonate 
• 173994-32-6 3-(pyridine-2-yldisulfanyl)propan-1-ol 
• 119577-16-1 (1-hydroxy)ethyl (+/-)-sec-phenylethyl thioether 
• 205698-60-8 1-triphenylsiloxy-propane-3-thiol 

Related news

Domain structure of binary self-assembled monolayers composed of 3-MERCAPTO-1-PROPANOL (cas 19721-22-3) and 1-tetradecanethiol on Au(1 1 1) prepared by coadsorption09/02/2019

The structure of the domains of phase-separated binary self-assembled monolayers (SAMs) composed of 3-mercapto-1-propanol and 1-tetradecanethiol (TDT) on Au(1 1 1) strongly depends on the thiol concentration of the solution from which the SAM is formed. Cyclic voltammograms and scanning tunnelin...detailed

Regular paperThe chemistry of 3-MERCAPTO-1-PROPANOL (cas 19721-22-3) with group 4 metallocene derivatives. The molecular structure of Cp2∗ZrCl(OCH2CH2CH2SH)09/01/2019

Titanocene or permethylzirconocene dichloride reacts with 1 molar equivalent of 3-mercapto-1-propanol (HOCH2CH2CH2SH) in the presence of NEt3 to give the monomeric chelate complex Cp2Ti(OCH2CH2CH2S) (1) or the oxygen-bonded monomeric complex Cp2∗ZrCl(OCH2CH2CH2SH) (2), respectively. When Cp2∗Zr(...detailed

Lipase-catalyzed chemospecific O-acylation of 3-MERCAPTO-1-PROPANOL (cas 19721-22-3) and 4-mercapto-1-butanol08/31/2019

The lipase-catalyzed chemospecific O-acylation of 3-mercapto-1-propanol and 4-mercapto-1-butanol by several aliphatic carboxylic acid ethyl esters are described. Similar treatment on 1-mercapto-2-propanol and 3-mercapto-2-butanol did not yield the expected O-acyl derivatives.detailed

Relevant articles and documents

2-mercaptoethanol synthesis

A process comprising reacting, in a reactor having a fixed bed containing a solid catalyst which contains a zeolite, hydrogen sulfide and an oxirane in the presence of the solid catalyst to yield a reaction product with contains a mercapto-alcohol. A reactor system includes the reactor, an oxirane feed stream, a hydrogen sulfide feed stream, a fixed bed containing the solid catalyst placed inside the reactor, and an effluent stream containing the reaction product. The hydrogen sulfide and the oxirane are present in a mole ratio in a range of about 5:1 to 50:1.

PROCESS FOR PRODUCING 3-MERCAPTO-1-PROPANOL

3-Mercapto-1-propanol can be produced in high yield without using pyrophoric aluminum lithium hydride, by subjecting a compound of the following formula (1) to addition reaction with allyl alcohol to prepare a compound of the following formula (2) and then hydrolyzing the compound of the following formula (2) into 3-mercapto-1-propanol: wherein R1 is an alkyl group.

7-(2-AMINOETHYL) BENZOTHIAZOLONES

There are disclosed compounds of formula I, Ar--CH. sub.2 CH 2--NH--CR 1 R 2--X--Y I in whichAr represents a group, STR1 X represents a C. sub.1-12 alkylene chain optionally interrupted or terminated by one or more groups selected from--S(O) n--,--O--,--C(Z)--, CR 6 R. sup.7, phenylmethyne,--NR 8--,--CONH--,--NHCO--and--NHCONH--, Y represents an optionally substituted aryl or cycloalkyl group,Z represents O or S, R 1, R 2, R 5 and R 9 each independently represent hydrogen or alkyl C 1-6,R 3 and R 4 represent hydrogen, or R. sup.3 and R 4 together form a group--S--,--NR 9--or--CH 2--,R 6 and R 7 independently represent hydrogen, alkyl C 1-6, fluoro, cyano, or CF. sub.3, provided that at least one of R 6 and R 7 is other than hydrogen,R 8 represents hydrogen or alkyl C 1-6, or when X is interrupted or terminated by more than one--NR 8--group may together with another R 8 group form the chain--CH 2--CH 2--, andn represents 0, 1 or 2,and pharmaceutically acceptable derivatives thereof.Processes for their production and pharmaceutical compositions and methods of treatment involving their use are also described.