197229-72-4

Upstream product

• 21930-98-3 (S)-2-amino-4-methyl-N-phenylpentanamide 
• 177218-78-9 (2S,4R)-2-[4-(1-Oxo-1,3-dihydro-isoindol-2-yl)-butyl]-4-[2-(4-propyl-phenyl)-ethyl]-pentanedioic acid 5-benzyl ester 1-tert-butyl ester 
• 162734-31-8 3-(4-(4-(1-n-Propyl)phenyl)butanoyl)-4(S)-phenylmethyl-2-oxazolidinone 
• 162734-32-9 (R)-2-[2-(4-Propyl-phenyl)-ethyl]-pentanedioic acid 5-tert-butyl ester 
• 103-65-1 phenylpropane 

Relevant academic research and scientific papers

Orally active inhibitors of stromelysin-1 (MMP-3)

Further development of N-carboxyalkyl dipeptide inhibitors of stromelysin-1 (MMP-3) led to the discovery of C-carboxyalkyl dipeptide analogs with improved oral bioavailability. An in vivo assay of human MMP-3 mediated degradation of a macromolecular substrate in an extravascular space is described and inhibition studies are reported.