19725-41-8

Upstream product

• 19725-36-1 7-hydroxy-3-(2-hydroxyphenyl)-4H-chromen-4-one 
• 74-88-4 methyl iodide 
• 19725-40-7 7-methoxy-3-(2-methoxyphenyl)-4H-chromen-4-one 
• 116081-96-0 2'-benzyloxy-7-methoxyisoflavone 
• 552-41-0 1-(2-hydroxy-4-methoxyphenyl)ethanone 
• 289636-10-8 2-benzyloxy-2'-hydroxy-4'-methoxy-chalcone 
• 18440-00-1 2-Hydroxy-4-methoxyphenyl 2-methoxybenzyl ketone 
• 1263202-67-0 1-(2,4-dimethoxyphenyl)-2-(2'-methoxyphenyl)-2-hydroxymethylene-1-ethanone 
• 28033-63-8 2-(2-methoxyphenyl)acetyl chloride 
• 93-25-4 2-methoxyphenylacetic acid 
• 101595-27-1 2,4,2'-trimethoxy-deoxybenzoin 
• 89466-08-0 2-hydroxyphenyl boronic acid 
• 73220-42-5 3-iodo-7-methoxy-chromen-4-one 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 

Downstream Products

• 110060-77-0 3-(2-ethoxy-phenyl)-7-methoxy-chromen-4-one 
• 62536-79-2 2'-acetoxy-7-methoxy-isoflavone 
• 116081-96-0 2'-benzyloxy-7-methoxyisoflavone 
• 62924-10-1 2-(2,4-dimethoxyphenyl)benzofuran 
• 101595-27-1 2,4,2'-trimethoxy-deoxybenzoin 
• 101743-69-5 2'-ethoxy-2,4-dimethoxy-deoxybenzoin 
• 112198-31-9 2'-benzyloxy-2-hydroxy-4-methoxy-deoxybenzoin 
• 102560-32-7 2'-benzyloxy-2,4-dimethoxy-deoxybenzoin 
• 19725-36-1 7-hydroxy-3-(2-hydroxyphenyl)-4H-chromen-4-one 

Relevant academic research and scientific papers

Development of a general approach to the synthesis of a library of isoflavonoid derivatives

Isoflavonoids are a class of organic compounds that act primarily as antioxidants. They are produced almost exclusively by various members of the bean family including soybeans, tofu, peanuts, chick peas, and alfalfa. The antioxidant characteristics that isoflavonoids exhibit help hinder the progression of certain cancers, primarily breast, prostate, and colon cancer. We have developed a three-five step synthesis for obtaining a suite of isoflavonoid derivatives. The synthesis involves an enamine formation, a ring closure and halogenation, a Suzuki coupling, and finally a global deprotection to obtain the respective isoflavonoid derivatives.

USE OF PTEROCARPANS AS ACTIVE ANTI-CELLULITE INGREDIENTS

The invention relates to a cosmetic, dermatological or pharmaceutical preparation, containing one, two or more compounds of formula (I) and/or a pharmaceutically acceptable salt of a compound of this type, (i) for use in a method for preventing, treating

Synthesis and anti-platelet, anti-inflammatory and anti- allergic activities of methoxyisoflavanquinone and related compounds

In a continuation of our search for novel anti-platelet agents, isoflavone quinone and isoflavanquinone were selected as lead compounds and the synthesis of their methoxy derivatives was carried out. Among them, the 4'- and 7-methoxy derivatives were successfully prepared, whereas the attempt to obtain 3'-methoxy derivatives resulted in their isomers, 3'-methoxyflavone quinone and 3'-methoxyflavanquinone, instead. After screening for their anti-platelet, anti-inflammatory and anti-allergic activities, a preliminary structure-activity relationship was established. Compounds 6c, 7a - c, 8c and 9a - c were found to exhibit significant activities. In particular, compound 7c demonstrated very potent anti-platelet, anti-inflammatory and anti-allergic activities and was then recommended for further pharmacological investigation.