19734-15-7Relevant academic research and scientific papers
Synthesis of α-aryl-diazophosphonates via palladium-catalyzed cross-coupling of aryl iodides with diethyl diazomethylphosphonate
Kosobokov, Mikhail D.,Titanyuk, Igor D.,Beletskaya, Irina P.
, p. 6791 - 6794 (2014)
An efficient procedure for the Pd-catalyzed arylation of diethyl α-diazomethylphosphonate with aryl iodides is described. It can serve as a pathway for the generation of arylated diazophosphonates, which are typically difficult to access. The significance of this methodology was demonstrated via further synthetic transformations of newly synthesized diazo compounds in cyclopropanation, epoxidation, N-H and O-H insertion reactions.
