197368-84-6Relevant academic research and scientific papers
Structure-activity study of 2,3-benzodiazepin-4-ones noncompetitive AMPAR antagonists: Identification of the 1-(4-amino-3-methylphenyl)-3,5-dihydro-7,8-ethylenedioxy-4H-2,3-benzodiazepin-4-one as neuroprotective agent
Micale, Nicola,Colleoni, Simona,Postorino, Giovanna,Pellicano, Alessia,Zappala, Maria,Lazzaro, John,Diana, Valentina,Cagnotto, Alfredo,Mennini, Tiziana,Grasso, Silvana
, p. 2200 - 2211 (2008/12/20)
In the search for AMPA receptor (AMPAR) antagonists, 2,3-benzodiazepines represent a family of specific noncompetitive antagonists with anticonvulsant and neuroprotective properties. We have previously shown that 2,3-benzodiazepin-4-ones possess marked an
