197379-02-5Relevant academic research and scientific papers
Synthesis of silicon-containing α-amino acids and hydantoins
Smith, Richard J.,Bratovanov, Svetoslav,Bienz, Stefan
, p. 13695 - 13702 (2007/10/03)
Three new silicon containing α-amino acids 6a-c and their respective hydantoin derivatives 8a-c have been prepared in racemic form. Alkylation of an α-amino cyanoacetate derivative with iodomethyl-substituted silanes, followed by hydrolysis gave the amino acids, and the subsequent reactions with KOCN and with HCl gave the hydantoins. The hydantoins are planned to be subjected to a biotechnological deracemization process.
