197449-36-8Relevant academic research and scientific papers
2,3-Dideoxy hex-2-enopyranosid-4-uloses as promising new anti-tubercular agents: Design, synthesis, biological evaluation and SAR studies
Saquib, Mohammad,Husain, Irfan,Sharma, Smriti,Yadav, Garima,Singh, Vipul K.,Sharma, Sandeep K.,Shah, Priyanka,Siddiqi, Mohammad Imran,Kumar, Brijesh,Lal, Jawahar,Jain, Girish K.,Srivastava, Brahm S.,Srivastava, Ranjana,Shaw, Arun K.
, p. 2217 - 2223 (2011/06/22)
The alarming resurgence of tuberculosis (TB) underlines the urgent need for development of new and potent anti-TB drugs. Towards this goal we herein report the design and synthesis of 2,3-dideoxy hex-2-enopyranosid-4-uloses as promising new anti-tubercula
A Chemo-Enzymatic Synthesis of D-Allosamine Derivatives from Tri-O-acetyl- D-glucal
Sugai, Takeshi,Okazaki, Hanako,Kuboki, Atsuhito,Ohta, Hiromichi
, p. 2535 - 2540 (2007/10/03)
N-Acetyl-D-allosamine and its derivatives were synthesized from tri-O-acetyl-D-glucal based on lipase-catalyzed selective protection of primary alcohols, [3,3] sigmatropic rearrangement of allylic trichloroacetimidates, and stereo- selective ruthenium-catalyzed dihydroxylation. In the course of this study, it was revealed that the Pseudomonas lipase- catalyzed acetylation occurred in a high yield (> 90%) exclusively at the primary alcohols of three Ferrier rearrangement products derived from tri-O-acetyl-D-glucal.
