197449-36-8Relevant academic research and scientific papers
2,3-Dideoxy hex-2-enopyranosid-4-uloses as promising new anti-tubercular agents: Design, synthesis, biological evaluation and SAR studies
Saquib, Mohammad,Husain, Irfan,Sharma, Smriti,Yadav, Garima,Singh, Vipul K.,Sharma, Sandeep K.,Shah, Priyanka,Siddiqi, Mohammad Imran,Kumar, Brijesh,Lal, Jawahar,Jain, Girish K.,Srivastava, Brahm S.,Srivastava, Ranjana,Shaw, Arun K.
scheme or table, p. 2217 - 2223 (2011/06/22)
The alarming resurgence of tuberculosis (TB) underlines the urgent need for development of new and potent anti-TB drugs. Towards this goal we herein report the design and synthesis of 2,3-dideoxy hex-2-enopyranosid-4-uloses as promising new anti-tubercula
A Chemo-Enzymatic Synthesis of D-Allosamine Derivatives from Tri-O-acetyl- D-glucal
Sugai, Takeshi,Okazaki, Hanako,Kuboki, Atsuhito,Ohta, Hiromichi
, p. 2535 - 2540 (2007/10/03)
N-Acetyl-D-allosamine and its derivatives were synthesized from tri-O-acetyl-D-glucal based on lipase-catalyzed selective protection of primary alcohols, [3,3] sigmatropic rearrangement of allylic trichloroacetimidates, and stereo- selective ruthenium-catalyzed dihydroxylation. In the course of this study, it was revealed that the Pseudomonas lipase- catalyzed acetylation occurred in a high yield (> 90%) exclusively at the primary alcohols of three Ferrier rearrangement products derived from tri-O-acetyl-D-glucal.
