197461-28-2

Upstream product

• 300807-55-0 2,4-bis(trimethylacetamido)-5-bromomethyl-6-bromothieno[2,3-d]pyrimidine 
• 197461-34-0 2,4-bis(trimethylacetamido)-5-methylthieno[2,3-d]pyrimidine 
• 93516-62-2 N-(2,6-dichloro-4-nitrophenyl)pyrrole 
• 93516-63-3 N-(2,6-dichloro-4-aminophenyl)pyrrole 
• 74195-50-9 2,4-diamino-5-methylthieno[2,3-d]pyrimidine 
• 99-30-9 4-nitro-2,6-dichloroaniline 
• 1026159-21-6 N-[6-Bromo-5-[(3,5-dichloro-4-pyrrol-1-yl-phenylamino)-methyl]-2-(2,2-dimethyl-propionylamino)-thieno[2,3-d]pyrimidin-4-yl]-2,2-dimethyl-propionamide 

Relevant academic research and scientific papers

2,4-Diaminothieno[2,3-d]pyrimidine lipophilic antifolates as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase

Ten previously unreported 2,4-diaminothieno[2,3-d]pyrimidine lipophilic dihydrofolate reductase inhibitors were synthesized as potential inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase. Pivaloylation of 2,4-diamino-5-methy