197574-99-5

Upstream product

• 1125-88-8 benzaldehyde dimethyl acetal 
• 197574-95-1 2-naphthylmethyl 2-acetamido-2-deoxy-β-D-glucopyranoside 
• 3068-34-6 Acetic acid (2R,3S,4R,5R,6R)-3-acetoxy-2-acetoxymethyl-5-acetylamino-6-chloro-tetrahydro-pyran-4-yl ester 
• 190181-66-9 (2-naphthyl)methyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside 
• 1592-38-7 2-Naphthalenemethanol 

Downstream Products

• 197575-03-4 (R)-2-[(4aR,6R,7R,8R,8aS)-7-Acetylamino-6-(naphthalen-2-ylmethoxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy]-propionic acid 

Relevant academic research and scientific papers

Syntheses of fluorine-containing mucin core 2/core 6 structures using novel fluorinated glucosaminyl donors

Syntheses of fluorinated mucin core 6 disaccharides and core 2 trisaccharides modified at the C-3 or C-4 position of the pertinent glucosamine residue required for mechanistic study of glycosyltransferases and sulfotransferases involved in the biosynthesi

Combinatorial libraries of monosaccharides

A monosaccharide compound of formula I as shown in the specification. Processes for the preparation of the compound of formula I and methods of screening for antibacterial or antibiotic compounds involving the compound of formula I.

Synthesis of hydrophobic derivatives of muramyldipeptides

Methyl esters of the cyclohexyl-, phenethyl-, (2-naphthyl)methyl-, and 2′-(1-naphthyl)ethyl β-glycosides of N-acetylmuramyl-L-alanyl-D-isoglutamine have been synthesized. The corresponding glycosides of N-acetylglucosamine were obtained by glycosylating the alcohols with the peracetate of α-glucosaminyl chloride in the presence of HgI2, followed by deacetylation. Subsequent benzylidenation and alkylation with α-L-chloropropionic acid led to glycosylmuramic acids, the condensation of which with the dipeptide and final debenzylidenation gave the desired glycopeptides.