197586-27-9Relevant academic research and scientific papers
A study of asymmetric protonation with chiral β-hydroxy sulfoxides. Asymmetric synthesis of (-)-epibatidine
Kosugi, Hiroshi,Abe, Makito,Hatsuda, Ryota,Uda, Hisashi,Kato, Michiharu
, p. 1857 - 1858 (2007/10/03)
The asymmetric synthesis of (-)-epibatidine 1, employing as the key step the asymmetric protonation of the achiral lithum enolate of cyclohexanone derivative 5 with chiral β-hydroxy sulfoxide 3b, is described.
