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11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine is a complex organic compound with the molecular formula C18H20N2S. It is a derivative of dibenzo[b,f][1,4]thiazepine, a tricyclic ring system consisting of two benzene rings fused to a thiazine ring. The compound features a 4-methylpiperazin-1-yl group attached to the 11th position of the dibenzo[b,f][1,4]thiazepine core, which contributes to its pharmacological properties. This specific chemical structure is known for its potential applications in the development of drugs targeting the serotonin system, particularly as a serotonin receptor agonist. Its synthesis and biological activity are of interest to researchers in the field of medicinal chemistry, as it may have implications for the treatment of various central nervous system disorders.

1977-09-9

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1977-09-9 Usage

Chemical class

Thiazepine

Type of drug

Tricyclic antidepressant

Common use

Treatment of depression and anxiety disorders

Mechanism of action

Increases levels of neurotransmitters (serotonin and norepinephrine) in the brain

Mode of action

Believed to involve the blockade of serotonin and norepinephrine reuptake

Side effects

Drowsiness, dizziness, dry mouth, and weight gain

Precaution

Use under the guidance of a healthcare professional

Target conditions

Mood improvement and reduction of depression symptoms

Pharmacological action

Enhances neurotransmission by blocking the reuptake of serotonin and norepinephrine

Structural feature

Contains a 4-methylpiperazin-1-yl group attached to the 11th position of the dibenzo[b,f][1,4]thiazepine core

Molecular weight

Approximately 343.5 g/mol

Appearance

Typically a solid, crystalline compound

Solubility

Soluble in organic solvents, such as ethanol and methanol, and slightly soluble in water

Stability

Stable under normal conditions, but should be stored in a cool, dry place and protected from light and moisture to maintain potency.

Check Digit Verification of cas no

The CAS Registry Mumber 1977-09-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,7 and 7 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1977-09:
(6*1)+(5*9)+(4*7)+(3*7)+(2*0)+(1*9)=109
109 % 10 = 9
So 1977-09-9 is a valid CAS Registry Number.

1977-09-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1977-09-9 SDS

1977-09-9Downstream Products

1977-09-9Relevant academic research and scientific papers

PESTICIDAL DIBENZO(HETERO)AZEPINE DERIVATIVES

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Page 66, (2010/02/07)

Use of compounds of formula (I): wherein X is S, O, S=O, SO2, NRa, or CRbRc;R1,R2 are halogen, OH, SH, NH2, CN, NO2, alkyl, alkoxy, alkylamino, dialkylamino, alkylthio

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